{"id":15885,"date":"2022-02-21T16:35:55","date_gmt":"2022-02-21T16:35:55","guid":{"rendered":"https:\/\/www.africa-press.net\/cameroun\/politique\/les-vaccins-a-arnm-creent-17-fois-plus-danticorps-neutralisants-que-limmunite-naturelle"},"modified":"2022-02-21T17:27:25","modified_gmt":"2022-02-21T17:27:25","slug":"les-vaccins-a-arnm-creent-17-fois-plus-danticorps-neutralisants-que-limmunite-naturelle","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/cameroun\/toutes-les-actualites\/les-vaccins-a-arnm-creent-17-fois-plus-danticorps-neutralisants-que-limmunite-naturelle","title":{"rendered":"Les vaccins \u00e0 ARNm cr\u00e9ent 17 fois plus d’anticorps neutralisants que l’immunit\u00e9 naturelle"},"content":{"rendered":"

Africa-Press – Cameroun. <\/strong><\/span>Une \u00e9tude r\u00e9cente compare les anticorps contre le SARS-CoV-2 issus de l’infection naturelle \u00e0 ceux produits par la vaccination avec une formule \u00e0 ARNm.<\/p>\n

Il existe deux moyens pour que l’immunit\u00e9 produise des anticorps contre le SARS-CoV-2 : \u00eatre vaccin\u00e9 ou \u00eatre infect\u00e9 naturellement par le virus. Les deux r\u00e9ponses immunitaires ne sont pas \u00e9quivalentes ; la nature des anticorps, leur quantit\u00e9 ou encore leur pouvoir neutralisant sont autant de param\u00e8tres \u00e9tudi\u00e9s et compar\u00e9s par les scientifiques. Le but n’est pas de d\u00e9terminer laquelle est la meilleure mais de comprendre ce qui les diff\u00e9rencie.<\/p>\n

Des anticorps vaccinaux plus nombreux et plus neutralisants<\/b><\/p>\n

Une \u00e9tude r\u00e9cente, parue dans Scientific Reports et men\u00e9e au sein de l’h\u00f4pital du National Institutes of Health, \u00e0 Bethseda, a \u00e9tudi\u00e9 les niveaux d’anticorps anti-RBD et leur pouvoir neutralisant dans le s\u00e9rum d’individus vaccin\u00e9s ou infect\u00e9s naturellement. Il appara\u00eet que le titre en anticorps anti-RBD apr\u00e8s l’injection d’un vaccin \u00e0 ARNm est 17 fois plus \u00e9lev\u00e9 qu’apr\u00e8s l’infection naturelle. Leur pouvoir neutralisant est aussi 17 fois plus important face \u00e0 un variant comportant la mutation N501Y, connue pour augmenter l’affinit\u00e9 du SARS-CoV-2 pour son r\u00e9cepteur pr\u00e9sent\u00e9 sur la cellule h\u00f4te.<\/p>\n

Nombreux et tr\u00e8s neutralisants, les anticorps vaccinaux semblent les plus efficaces pour lutter contre les variants du SARS-CoV-2 malgr\u00e9 les capacit\u00e9s d’\u00e9chappement de ces derniers. N\u00e9anmoins, l’\u00e9tude souffre de plusieurs manques : les tests de neutralisation sont simplifi\u00e9s et ne prennent pas en compte des param\u00e8tres complexes impliqu\u00e9s dans l’interaction SARS-CoV-2 – cellule h\u00f4te (nombre de r\u00e9cepteurs \u00e0 la surface de la cellule, par exemple).<\/p>\n

De plus, l’analyse concernant les variants se concentre sur l’unique mutation N501Y. Si cette mutation a un r\u00f4le central dans l’\u00e9chappement au syst\u00e8me immunitaire des variants qui la porte, ce n’est pas la seule. Uniques ou combin\u00e9es, d’autres mutations influent sur la reconnaissance des anticorps et leur pouvoir neutralisant.<\/p>\n

L’immunit\u00e9 apr\u00e8s une infection naturelle varie beaucoup entre les individus, certains d\u00e9veloppent de grande quantit\u00e9 d’anticorps, d’autres non. Dans les \u00e9chantillons analys\u00e9s ici, l’immunit\u00e9 naturelle persiste environ neuf mois contre six mois pour l’immunit\u00e9 vaccinale. Mais, pour se pr\u00e9munir de la Covid-19, la vaccination est toujours la solution la plus raisonnable ; ses effets secondaires graves sont rares et temporaires. L’infection naturelle expose, elle, \u00e0 des risques importants de Covid-19 s\u00e9v\u00e8res, mais aussi \u00e0 des sympt\u00f4mes handicapants sur le long terme encore mal pris en charge par les m\u00e9decins.<\/p>\n

Pour plus d’informations et d’analyses sur la Cameroun<\/a>, suivez Africa-Press<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Africa-Press – Cameroun. Une \u00e9tude r\u00e9cente compare les anticorps contre le SARS-CoV-2 issus de l’infection naturelle \u00e0 ceux produits par la vaccination avec une formule \u00e0 ARNm. Il existe deux moyens pour que l’immunit\u00e9 produise des anticorps contre le SARS-CoV-2 : \u00eatre vaccin\u00e9 ou \u00eatre infect\u00e9 naturellement par le virus. Les deux r\u00e9ponses immunitaires ne […]<\/p>\n","protected":false},"author":82,"featured_media":15884,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[21,11,10],"tags":[36,50,49],"class_list":["post-15885","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-communaute","category-homepage-french","category-toutes-les-actualites","tag-africa-press","tag-africa-press-cameroun","tag-cameroun"],"yoast_head":"\nLes vaccins \u00e0 ARNm cr\u00e9ent 17 fois plus d'anticorps neutralisants que l'immunit\u00e9 naturelle - Cameroun<\/title>\n<meta name=\"description\" content=\"Une \u00e9tude r\u00e9cente compare les anticorps contre le SARS-CoV-2 issus de l'infection naturelle \u00e0 ceux produits par la vacci ...\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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