{"id":10671,"date":"2023-03-23T12:59:17","date_gmt":"2023-03-23T12:59:17","guid":{"rendered":"https:\/\/www.africa-press.net\/djibouti\/politique\/les-mille-visages-du-diabete-de-type-2"},"modified":"2023-03-23T14:03:29","modified_gmt":"2023-03-23T14:03:29","slug":"les-mille-visages-du-diabete-de-type-2","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/djibouti\/toutes-les-actualites\/les-mille-visages-du-diabete-de-type-2","title":{"rendered":"Les mille visages du diab\u00e8te de type 2"},"content":{"rendered":"

Africa-Press – Djibouti. <\/strong><\/span>La preuve avec une session intitule\u0301e \u00ab\u00a0les mille visages du diabe\u0300te de type 2 (DT2)\u00a0\u00bb pre\u0301sente\u0301e lors de la 16e e\u0301dition du congre\u0300s 2023 de la Socie\u0301te\u0301 francophone du diabe\u0300te (SFD) qui se de\u0301roule du 21 au 24 mars 2023 a\u0300 Montpellier.<\/p>\n

\u00ab\u00a0La communaute\u0301 des endocrinologues n\u2019est pas unanime sur ce qu\u2019est le diabe\u0300te de type 2\u00a0\u00bb<\/b><\/p>\n

Cette affection, qui concerne 8% de la population en France, s\u2019ave\u0300re de\u0301cide\u0301ment tre\u0300s he\u0301te\u0301roge\u0300ne. On connaissait le diabe\u0300te de type 1 (DT1), de\u0301butant pluto\u0302t dans l\u2019enfance, et celui de type 2 (DT2) survenant a\u0300 l\u2019a\u0302ge adulte. Mais cette distinction, longtemps base\u0301e entre autres sur l\u2019a\u0302ge et le poids, le DT1 e\u0301tant pluto\u0302t marque\u0301 par un amaigrissement et le DT2 par un surpoids ou une obe\u0301site\u0301, ne suffit plus. \u00ab\u00a0Surtout aujourd\u2019hui avec une pre\u0301valence d\u2019environ 18% de l\u2019obe\u0301site\u0301 dans les deux groupes\u00a0\u00bb, pre\u0301cise le Pr Jean-Franc\u0327ois Gauthier, diabe\u0301tologue a\u0300 l\u2019ho\u0302pital Lariboisie\u0300re (Paris). Or, au quotidien, les diabe\u0301tologues perc\u0327oivent bien l\u2019he\u0301te\u0301roge\u0301ne\u0301ite\u0301 de leurs malades atteints de DT2 : le mode de de\u0301couverte, les types de complications…<\/p>\n

\u00ab\u00a0La communaute\u0301 des endocrinologues n\u2019est en effet pas unanime sur ce qu\u2019est le DT2\u00a0\u00bb, souligne le Pr Etienne Larger, chef du service de diabe\u0301tologie de l’ho\u0302pital Cochin (Paris) lors de sa pre\u0301sentation a\u0300 la SFD. Et ce spe\u0301cialiste de citer un e\u0301ditorial provocateur paru il y a de\u0301ja\u0300 10 ans, en 2013, dans la revue Lancet qui s\u2019interrogeait sur l\u2019existence re\u0301elle de la cate\u0301gorie du DT2 (\u00ab\u00a0Is type 2 diabetes a category error?\u00a0\u00bb).<\/p>\n

Depuis, une re\u0301flexion a de\u0301marre\u0301 en ce sens, en particulier dans le nord de l\u2019Europe ou\u0300 une e\u0301quipe a voulu stratifier les patients en sous-groupes. Pour quelle raison ? Affiner les traitements pour en faire profiter au plus to\u0302t les patients les plus fragiles, ceux a\u0300 tre\u0300s haut risque de complications.<\/p>\n

Ces travaux scandinaves ont e\u0301te\u0301 publie\u0301s en 2018 dans le Lancet et reposent sur une analyse bio-informatique de plusieurs variables comme l\u2019a\u0302ge, l\u2019indice de masse corporelle, le dosage d\u2019he\u0301moglobine dite glyque\u0301e (une fraction de l\u2019he\u0301moglobine ayant fixe\u0301 du sucre et dite HBA1c) et le calcul de diffe\u0301rents index dits HOMA (Homeostasis Model Accessment of insuline resistance) e\u0301tablis a\u0300 partir des valeurs de la glyce\u0301mie et de l\u2019insuline.<\/p>\n

\u00ab\u00a0Ce classement constitue un premier pas vers une me\u0301decine de pre\u0301cision dans le diabe\u0300te\u00a0\u00bb<\/b><\/p>\n

Les chercheurs ont ainsi pu identifier cinq clusters de patients, autant de sous-groupes posse\u0301dant des profils de risques diffe\u0301rents :<\/p>\n

Le cluster 1 (6% des patients) regroupe les personnes pre\u0301sentant une maladie de\u0301tectable par la pre\u0301sence d\u2019autoanticorps, soit l\u2019e\u0301quivalent d\u2019un diabe\u0300te de type 1 (DT1).<\/p>\n

Le cluster 2 (18%) pre\u0301sente le risque le plus e\u0301leve\u0301 de complications tant oculaires que re\u0301nales.<\/p>\n

Le cluster 3 (15%) est lui plus marque\u0301 par des risques cardiovasculaires.<\/p>\n

Le cluster 4 (22%) est plus en lien avec l\u2019obe\u0301site\u0301.<\/p>\n

Le cluster 5 (39%) concerne surtout les sujets a\u0302ge\u0301s.<\/p>\n

Autant de donne\u0301es confirme\u0301es depuis par des travaux allemands. \u00ab\u00a0Ce nouveau classement constitue un premier pas vers une me\u0301decine de pre\u0301cision dans le diabe\u0300te\u00a0\u00bb, commentaient les auteurs sue\u0301dois dans leur publication. Reste a\u0300 de\u0301montrer que cette nouvelle classification se concre\u0301tisera par des strate\u0301gies the\u0301rapeutiques diffe\u0301rentes.<\/p>\n

\u00ab\u00a0Inte\u0301re\u0302t scientifique the\u0301orique ou re\u0301alite\u0301 pratique ?\u00a0\u00bb, re\u0301sume le Dr Sandrine Lablanche, endocrinologue au CHU Grenoble Alpes. Le temps seul permettra de re\u0301pondre a\u0300 cette question car de\u0301ja\u0300, \u00ab\u00a0le suivi des clusters de\u0301montre que cinq ans apre\u0300s, un patient sur cinq a change\u0301 de cluster\u00a0\u00bb, pointe le Dr Lablanche ! De\u0301cide\u0301ment, tout se complique dans le DT2.<\/p>\n

Pour plus d’informations et d’analyses sur la Djibouti<\/a>, suivez Africa-Press<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Africa-Press – Djibouti. La preuve avec une session intitule\u0301e \u00ab\u00a0les mille visages du diabe\u0300te de type 2 (DT2)\u00a0\u00bb pre\u0301sente\u0301e lors de la 16e e\u0301dition du congre\u0300s 2023 de la Socie\u0301te\u0301 francophone du diabe\u0300te (SFD) qui se de\u0301roule du 21 au 24 mars 2023 a\u0300 Montpellier. \u00ab\u00a0La communaute\u0301 des endocrinologues n\u2019est pas unanime sur ce qu\u2019est […]<\/p>\n","protected":false},"author":82,"featured_media":10670,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[22,10],"tags":[36,49,50],"class_list":["post-10671","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divers","category-toutes-les-actualites","tag-africa-press","tag-africa-press-djibouti","tag-djibouti"],"yoast_head":"\nLes mille visages du diab\u00e8te de type 2 - Djibouti<\/title>\n<meta name=\"description\" content=\"La preuve avec une session intitule\u0301e "les mille visages du diabe\u0300te de type 2 (DT2)" pre\u0301sente\u0301e lors de la 16e e\u0301ditio ...\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.africa-press.net\/djibouti\/toutes-les-actualites\/les-mille-visages-du-diabete-de-type-2\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Les mille visages du diab\u00e8te de type 2\" \/>\n<meta property=\"og:description\" content=\"La preuve avec une session intitule\u0301e "les mille visages du diabe\u0300te de type 2 (DT2)" pre\u0301sente\u0301e lors de la 16e e\u0301ditio ...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.africa-press.net\/djibouti\/toutes-les-actualites\/les-mille-visages-du-diabete-de-type-2\" \/>\n<meta property=\"og:site_name\" content=\"Djibouti\" \/>\n<meta property=\"article:published_time\" content=\"2023-03-23T12:59:17+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-03-23T14:03:29+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/static.africa-press.net\/djibouti\/sites\/52\/2023\/03\/postQueueImg_1679560193.27.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"898\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"cfeditorfr\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"cfeditorfr\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.africa-press.net\/djibouti\/toutes-les-actualites\/les-mille-visages-du-diabete-de-type-2#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.africa-press.net\/djibouti\/toutes-les-actualites\/les-mille-visages-du-diabete-de-type-2\"},\"author\":{\"name\":\"cfeditorfr\",\"@id\":\"https:\/\/www.africa-press.net\/djibouti\/#\/schema\/person\/2b1cf3cd81a31e3cd26889ca66d677f1\"},\"headline\":\"Les mille visages du diab\u00e8te de type 2\",\"datePublished\":\"2023-03-23T12:59:17+00:00\",\"dateModified\":\"2023-03-23T14:03:29+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.africa-press.net\/djibouti\/toutes-les-actualites\/les-mille-visages-du-diabete-de-type-2\"},\"wordCount\":690,\"commentCount\":0,\"image\":{\"@id\":\"https:\/\/www.africa-press.net\/djibouti\/toutes-les-actualites\/les-mille-visages-du-diabete-de-type-2#primaryimage\"},\"thumbnailUrl\":\"https:\/\/static.africa-press.net\/djibouti\/sites\/52\/2023\/03\/postQueueImg_1679560193.27.jpg\",\"keywords\":[\"Africa Press\",\"Africa Press-Djibouti\",\"Djibouti\"],\"articleSection\":[\"Divers\",\"Toutes les actualit\u00e9s\"],\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.africa-press.net\/djibouti\/toutes-les-actualites\/les-mille-visages-du-diabete-de-type-2#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.africa-press.net\/djibouti\/toutes-les-actualites\/les-mille-visages-du-diabete-de-type-2\",\"url\":\"https:\/\/www.africa-press.net\/djibouti\/toutes-les-actualites\/les-mille-visages-du-diabete-de-type-2\",\"name\":\"Les mille visages du diab\u00e8te de type 2 - 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