{"id":4505,"date":"2022-10-31T19:22:36","date_gmt":"2022-10-31T19:22:36","guid":{"rendered":"https:\/\/www.africa-press.net\/guinee-equatoriale\/politique\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers"},"modified":"2022-10-31T21:37:11","modified_gmt":"2022-10-31T21:37:11","slug":"ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers","title":{"rendered":"Ce m\u00e9dicament en test peut bloquer la croissance des cancers"},"content":{"rendered":"

Africa-Press – Guinee Equatoriale. <\/strong><\/span>Le ge\u0300ne MYC, implique\u0301 dans le maintien de nombreux cancers, est une cible difficile a\u0300 combattre. A\u0300 l\u2019occasion d\u2019un congre\u0300s annuel espagnol, des chercheurs pre\u0301sentent actuellement les re\u0301sultats d\u2019un essai clinique pre\u0301coce concluant visant MYC.<\/p>\n

Pour la premie\u0300re fois, un me\u0301dicament a re\u0301ussi a\u0300 inhiber de manie\u0300re su\u0302re la fonction du ge\u0300ne MYC \u2014 implique\u0301 dans la croissance des tumeurs \u2013 lors d\u2019un essai clinique de phase I. \u00ab MYC est l\u2019une des cibles les plus recherche\u0301es dans le domaine du cancer, car elle joue un ro\u0302le cle\u0301 dans l\u2019apparition et le maintien de nombreux cancers humains courants, tels que le cancer du sein, de la prostate, du poumon et des ovaires \u00bb, a pre\u0301cise\u0301 la Docteur Elena Garralda lors du 34e congre\u0300s sur les cibles mole\u0301culaires et la the\u0301rapeutique du cancer qui se tient actuellement a\u0300 Barcelone, en Espagne.<\/p>\n

Comme pour tout essai clinique pre\u0301coce, un petit groupe de volontaires a e\u0301te\u0301 recrute\u0301 (22 personnes a\u0300 partir d\u2019avril 2021) afin d\u2019e\u0301valuer la se\u0301curite\u0301 du me\u0301dicament chez l\u2019Homme ainsi que ses premiers effets anti-tumoraux. Les chercheurs ont de\u0301veloppe\u0301 une prote\u0301ine appele\u0301e \u00ab OMO-103 \u00bb qui peut atteindre le noyau cellulaire, et qui avait de\u0301ja\u0300 montre\u0301 une capacite\u0301 a\u0300 bloquer MYC lors d\u2019expe\u0301riences sur les souris. La prote\u0301ine a e\u0301te\u0301 administre\u0301e par voie intraveineuse a\u0300 diffe\u0301rentes doses (de 0,48 a\u0300 9,72 mg par kg de poids du patient) et sur plusieurs semaines.<\/p>\n

Vers un essai clinique de phase II<\/p>\n

En pre\u0301levant des biopsies de tumeurs, les chercheurs ont constate\u0301 une stabilisation de la maladie chez certains patients, le traitement ayant stoppe\u0301 la croissance du cancer. Ils pre\u0301cisent que huit des douze patients qui ont subi un scanner apre\u0300s neuf semaines pre\u0301sentaient une maladie stable au 10 octobre 2022.<\/p>\n

En outre, les re\u0301sultats montrent que les volontaires ont ge\u0301ne\u0301ralement subi des effets secondaires le\u0301gers avec OMO-103 qui pourraient e\u0302tre associe\u0301s a\u0300 une chimiothe\u0301rapie ou d\u2019autres the\u0301rapies. Le me\u0301dicament est de\u0301sormais pre\u0302t a\u0300 passer a\u0300 un essai de phase II, avec une dose recommande\u0301e de 6,48 mg par kg.<\/p>\n

Pour plus d’informations et d’analyses sur la Guinee Equatoriale<\/a>, suivez Africa-Press<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Africa-Press – Guinee Equatoriale. Le ge\u0300ne MYC, implique\u0301 dans le maintien de nombreux cancers, est une cible difficile a\u0300 combattre. A\u0300 l\u2019occasion d\u2019un congre\u0300s annuel espagnol, des chercheurs pre\u0301sentent actuellement les re\u0301sultats d\u2019un essai clinique pre\u0301coce concluant visant MYC. Pour la premie\u0300re fois, un me\u0301dicament a re\u0301ussi a\u0300 inhiber de manie\u0300re su\u0302re la fonction du […]<\/p>\n","protected":false},"author":82,"featured_media":4504,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[22,10],"tags":[36,49,50],"class_list":["post-4505","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divers","category-toutes-les-actualites","tag-africa-press","tag-africa-press-guinee-equatoriale","tag-guinee-equatoriale"],"yoast_head":"\nCe m\u00e9dicament en test peut bloquer la croissance des cancers - Guin\u00e9e \u00e9quatoriale<\/title>\n<meta name=\"description\" content=\"Le ge\u0300ne MYC, implique\u0301 dans le maintien de nombreux cancers, est une cible difficile a\u0300 combattre. A\u0300 l\u2019occasion d\u2019un c ...\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ce m\u00e9dicament en test peut bloquer la croissance des cancers\" \/>\n<meta property=\"og:description\" content=\"Le ge\u0300ne MYC, implique\u0301 dans le maintien de nombreux cancers, est une cible difficile a\u0300 combattre. A\u0300 l\u2019occasion d\u2019un c ...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers\" \/>\n<meta property=\"og:site_name\" content=\"Guin\u00e9e \u00e9quatoriale\" \/>\n<meta property=\"article:published_time\" content=\"2022-10-31T19:22:36+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-10-31T21:37:11+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/static.africa-press.net\/guinee-equatoriale\/sites\/53\/2022\/10\/postQueueImg_2-63603fe8e1db6.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1520\" \/>\n\t<meta property=\"og:image:height\" content=\"791\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"cfeditorfr\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"cfeditorfr\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers\"},\"author\":{\"name\":\"cfeditorfr\",\"@id\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/#\/schema\/person\/2b1cf3cd81a31e3cd26889ca66d677f1\"},\"headline\":\"Ce m\u00e9dicament en test peut bloquer la croissance des cancers\",\"datePublished\":\"2022-10-31T19:22:36+00:00\",\"dateModified\":\"2022-10-31T21:37:11+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers\"},\"wordCount\":409,\"commentCount\":0,\"image\":{\"@id\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#primaryimage\"},\"thumbnailUrl\":\"https:\/\/static.africa-press.net\/guinee-equatoriale\/sites\/53\/2022\/10\/postQueueImg_2-63603fe8e1db6.jpg\",\"keywords\":[\"Africa Press\",\"Africa Press-Guinee Equatoriale\",\"Guinee Equatoriale\"],\"articleSection\":[\"Divers\",\"Toutes les actualit\u00e9s\"],\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers\",\"url\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers\",\"name\":\"Ce m\u00e9dicament en test peut bloquer la croissance des cancers - Guin\u00e9e \u00e9quatoriale\",\"isPartOf\":{\"@id\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#primaryimage\"},\"thumbnailUrl\":\"https:\/\/static.africa-press.net\/guinee-equatoriale\/sites\/53\/2022\/10\/postQueueImg_2-63603fe8e1db6.jpg\",\"datePublished\":\"2022-10-31T19:22:36+00:00\",\"dateModified\":\"2022-10-31T21:37:11+00:00\",\"author\":{\"@id\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/#\/schema\/person\/2b1cf3cd81a31e3cd26889ca66d677f1\"},\"description\":\"Le ge\u0300ne MYC, implique\u0301 dans le maintien de nombreux cancers, est une cible difficile a\u0300 combattre. A\u0300 l\u2019occasion d\u2019un c ...\",\"breadcrumb\":{\"@id\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#primaryimage\",\"url\":\"https:\/\/static.africa-press.net\/guinee-equatoriale\/sites\/53\/2022\/10\/postQueueImg_2-63603fe8e1db6.jpg\",\"contentUrl\":\"https:\/\/static.africa-press.net\/guinee-equatoriale\/sites\/53\/2022\/10\/postQueueImg_2-63603fe8e1db6.jpg\",\"width\":1520,\"height\":791,\"caption\":\"Ce m\u00e9dicament en test peut bloquer la croissance des cancers\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Ce m\u00e9dicament en test peut bloquer la croissance des cancers\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/#website\",\"url\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/\",\"name\":\"Guin\u00e9e \u00e9quatoriale\",\"description\":\"Just another Africa News Agency Sites site\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.africa-press.net\/guinee-equatoriale\/#\/schema\/person\/2b1cf3cd81a31e3cd26889ca66d677f1\",\"name\":\"cfeditorfr\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Ce m\u00e9dicament en test peut bloquer la croissance des cancers - Guin\u00e9e \u00e9quatoriale","description":"Le ge\u0300ne MYC, implique\u0301 dans le maintien de nombreux cancers, est une cible difficile a\u0300 combattre. A\u0300 l\u2019occasion d\u2019un c ...","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers","og_locale":"fr_FR","og_type":"article","og_title":"Ce m\u00e9dicament en test peut bloquer la croissance des cancers","og_description":"Le ge\u0300ne MYC, implique\u0301 dans le maintien de nombreux cancers, est une cible difficile a\u0300 combattre. A\u0300 l\u2019occasion d\u2019un c ...","og_url":"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers","og_site_name":"Guin\u00e9e \u00e9quatoriale","article_published_time":"2022-10-31T19:22:36+00:00","article_modified_time":"2022-10-31T21:37:11+00:00","og_image":[{"width":1520,"height":791,"url":"https:\/\/static.africa-press.net\/guinee-equatoriale\/sites\/53\/2022\/10\/postQueueImg_2-63603fe8e1db6.jpg","type":"image\/jpeg"}],"author":"cfeditorfr","twitter_card":"summary_large_image","twitter_misc":{"\u00c9crit par":"cfeditorfr","Dur\u00e9e de lecture estim\u00e9e":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#article","isPartOf":{"@id":"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers"},"author":{"name":"cfeditorfr","@id":"https:\/\/www.africa-press.net\/guinee-equatoriale\/#\/schema\/person\/2b1cf3cd81a31e3cd26889ca66d677f1"},"headline":"Ce m\u00e9dicament en test peut bloquer la croissance des cancers","datePublished":"2022-10-31T19:22:36+00:00","dateModified":"2022-10-31T21:37:11+00:00","mainEntityOfPage":{"@id":"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers"},"wordCount":409,"commentCount":0,"image":{"@id":"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#primaryimage"},"thumbnailUrl":"https:\/\/static.africa-press.net\/guinee-equatoriale\/sites\/53\/2022\/10\/postQueueImg_2-63603fe8e1db6.jpg","keywords":["Africa Press","Africa Press-Guinee Equatoriale","Guinee Equatoriale"],"articleSection":["Divers","Toutes les actualit\u00e9s"],"inLanguage":"fr-FR","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers","url":"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers","name":"Ce m\u00e9dicament en test peut bloquer la croissance des cancers - Guin\u00e9e \u00e9quatoriale","isPartOf":{"@id":"https:\/\/www.africa-press.net\/guinee-equatoriale\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#primaryimage"},"image":{"@id":"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#primaryimage"},"thumbnailUrl":"https:\/\/static.africa-press.net\/guinee-equatoriale\/sites\/53\/2022\/10\/postQueueImg_2-63603fe8e1db6.jpg","datePublished":"2022-10-31T19:22:36+00:00","dateModified":"2022-10-31T21:37:11+00:00","author":{"@id":"https:\/\/www.africa-press.net\/guinee-equatoriale\/#\/schema\/person\/2b1cf3cd81a31e3cd26889ca66d677f1"},"description":"Le ge\u0300ne MYC, implique\u0301 dans le maintien de nombreux cancers, est une cible difficile a\u0300 combattre. A\u0300 l\u2019occasion d\u2019un c ...","breadcrumb":{"@id":"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers"]}]},{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#primaryimage","url":"https:\/\/static.africa-press.net\/guinee-equatoriale\/sites\/53\/2022\/10\/postQueueImg_2-63603fe8e1db6.jpg","contentUrl":"https:\/\/static.africa-press.net\/guinee-equatoriale\/sites\/53\/2022\/10\/postQueueImg_2-63603fe8e1db6.jpg","width":1520,"height":791,"caption":"Ce m\u00e9dicament en test peut bloquer la croissance des cancers"},{"@type":"BreadcrumbList","@id":"https:\/\/www.africa-press.net\/guinee-equatoriale\/toutes-les-actualites\/ce-medicament-en-test-peut-bloquer-la-croissance-des-cancers#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/www.africa-press.net\/guinee-equatoriale\/"},{"@type":"ListItem","position":2,"name":"Ce m\u00e9dicament en test peut bloquer la croissance des cancers"}]},{"@type":"WebSite","@id":"https:\/\/www.africa-press.net\/guinee-equatoriale\/#website","url":"https:\/\/www.africa-press.net\/guinee-equatoriale\/","name":"Guin\u00e9e \u00e9quatoriale","description":"Just another Africa News Agency Sites site","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.africa-press.net\/guinee-equatoriale\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"},{"@type":"Person","@id":"https:\/\/www.africa-press.net\/guinee-equatoriale\/#\/schema\/person\/2b1cf3cd81a31e3cd26889ca66d677f1","name":"cfeditorfr"}]}},"_links":{"self":[{"href":"https:\/\/www.africa-press.net\/guinee-equatoriale\/wp-json\/wp\/v2\/posts\/4505","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.africa-press.net\/guinee-equatoriale\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.africa-press.net\/guinee-equatoriale\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.africa-press.net\/guinee-equatoriale\/wp-json\/wp\/v2\/users\/82"}],"replies":[{"embeddable":true,"href":"https:\/\/www.africa-press.net\/guinee-equatoriale\/wp-json\/wp\/v2\/comments?post=4505"}],"version-history":[{"count":0,"href":"https:\/\/www.africa-press.net\/guinee-equatoriale\/wp-json\/wp\/v2\/posts\/4505\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.africa-press.net\/guinee-equatoriale\/wp-json\/wp\/v2\/media\/4504"}],"wp:attachment":[{"href":"https:\/\/www.africa-press.net\/guinee-equatoriale\/wp-json\/wp\/v2\/media?parent=4505"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.africa-press.net\/guinee-equatoriale\/wp-json\/wp\/v2\/categories?post=4505"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.africa-press.net\/guinee-equatoriale\/wp-json\/wp\/v2\/tags?post=4505"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}