{"id":12780,"date":"2020-08-14T14:43:32","date_gmt":"2020-08-14T14:43:32","guid":{"rendered":"https:\/\/www.africa-press.com\/kenya\/?p=12780"},"modified":"2020-08-14T14:43:32","modified_gmt":"2020-08-14T14:43:32","slug":"scientists-still-puzzled-by-low-corona-deaths-in-africa","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/scientists-still-puzzled-by-low-corona-deaths-in-africa","title":{"rendered":"Scientists still puzzled by low corona deaths in Africa"},"content":{"rendered":"<p><strong>Author:\u00a0Linda Nordling\u00a0<\/strong><br \/>\n<strong>AfricaPress-Kenya:<\/strong> Although Africa reported its millionth official Covid-19 case last week, it seems to have weathered the pandemic relatively well so far, with fewer than one confirmed case for every thousand people and just 23,000 deaths so far. Yet several antibody surveys suggest far more Africans have been infected with the coronavirus \u2014 a discrepancy that is puzzling scientists around the continent.<\/p>\n<p>\u201cWe do not have an answer,\u201d says immunologist Sophie Uyoga at the Kenya Medical Research Institute-Wellcome Trust Research Programme.\u00a0After testing more than 3,000 blood donors, Uyoga and colleagues estimated in a\u00a0preprint\u00a0last month that one in 20 Kenyans aged 15 to 64 \u2014 or 1.6 million people \u2014 has antibodies to Sars-CoV-2, an indication of past infection.<\/p>\n<p>That would put Kenya on a par with\u00a0Spain in mid-May\u00a0when that country was descending from its coronavirus peak and had 27,000 official Covid-19 deaths. Kenya\u2019s official toll stood at 100 when the study ended. And Kenya\u2019s hospitals are not reporting huge numbers of people with Covid-19 symptoms.\u00a0Other antibody studies in Africa have yielded similarly surprising findings.<\/p>\n<p>From a\u00a0survey\u00a0of 500 asymptomatic health care workers in Blantyre, Malawi, immunologist Kondwani Jambo of the Malawi\u2013Liverpool Wellcome Trust Clinical Research Programme and colleagues concluded that up to 12.3 per cent of them had been exposed to the coronavirus.<\/p>\n<p>Based on those findings and mortality ratios for Covid-19 elsewhere, they estimated that the reported number of deaths in Blantyre at the time, 17, was eight times lower than expected.<\/p>\n<p>Scientists who surveyed about 10,000 people in the northeastern cities of Nampula and Pemba in Mozambique found antibodies to Sars-CoV-2 in\u00a0three per cent\u00a0to 10 per cent of participants, depending on their occupation; market vendors had the highest rates, followed by health workers.\u00a0Yet in Nampula, a city of approximately 750,000, a mere 300 infections had been confirmed at the time.<\/p>\n<p>Mozambique only has 16 confirmed Covid-19 deaths. Yap Boum, a microbiologist and epidemiologist with Epicentre Africa, the research and training arm of Doctors Without Borders, says he found a high prevalence of Sars-CoV-2 antibodies in people from Cameroon as well, a result that remains unpublished.<\/p>\n<ul class=\"list-group readmore my-3\">\n<li style=\"list-style-type: none\"><\/li>\n<\/ul>\n<p><strong>Antibody data<\/strong><\/p>\n<p>So what explains the huge gap between antibody data on the one hand and the official case and death counts on the other? Part of the reason may be that Africa misses many more cases than other parts of the world because it has far less testing capacity.\u00a0Kenya tests about one in every 10,000 inhabitants daily for active Sars-CoV-2 infections, one-tenth of the rate in Spain or Canada.<\/p>\n<p>Nigeria, the continent\u2019s most populous nation, tests one out of every 50,000 people per day. Even many people who die from Covid-19 may not get a proper diagnosis.\u00a0But in that case, you would still expect an overall rise in mortality, which Kenya has not seen, says pathologist Anne Barasa of the University of Nairobi who did not participate in the country\u2019s coronavirus antibody study.<\/p>\n<p>In South Africa, by contrast, the number of excess natural deaths reported between\u00a0May 6\u00a0and July 28\u00a0exceeded its official Covid-19 death toll by a factor of four to one.<\/p>\n<p>Uyoga, however, cautions that the pandemic has hamstrung Kenya\u2019s mortality surveillance system\u00a0as fieldworkers have been unable to move around.\u00a0Marina Poll\u00e1n of the Carlos III Health Institute in Madrid, who led Spain\u2019s antibody survey, says Africa\u2019s youthfulness may protect it. Spain\u2019s median age is 45; in Kenya and Malawi, it\u2019s 20 and 18, respectively.<\/p>\n<p>Young people around the world are far less likely to get severely ill or die from the virus. And the population in Kenya\u2019s cities, where the pandemic first took hold, skews even younger than the country as a whole, says Thumbi Mwangi, an epidemiologist at the University of Nairobi.<\/p>\n<p>The number of severe and fatal cases \u201cmay go higher when the disease has moved to the rural areas where we have populations with advanced age,\u201d he says.\u00a0Jambo is exploring the hypothesis that Africans have had more exposure to other coronaviruses that cause little more than colds in humans, which may provide some defense against Covid-19.<\/p>\n<p>Another possibility is that regular exposure to malaria or other infectious diseases could prime the immune system to fight new pathogens, including Sars-CoV-2, Boum adds. Barasa, on the other hand, suspects genetic factors protect the Kenyan population from severe disease.\u00a0More antibody surveys may help fill out the picture.<\/p>\n<p>A French-funded study will test thousands for antibodies in Guinea, Senegal, Benin, Ghana, Cameroon, and the Democratic Republic of the Congo; results are expected by October.\u00a0The studies will ensure good representation across populations, says Jean-Fran\u00e7ois Etard from France\u2019s Research Institute for Development, who is leading the study in Guinea jointly with a local scientist.<\/p>\n<p>And 13 labs in 11 African countries are participating in a global Sars-CoV-2 antibody survey coordinated by the World Health Organisation.\u00a0South Africa, meanwhile, plans to conduct a number of serological studies both in Covid-19 hotspots and the general population, says Lynn Morris, who leads the country\u2019s National Institute for Communicable Diseases.<\/p>\n<p>She notes that antibody prevalence found in the study will likely be an underestimate of true infection rates, given that the virus doesn\u2019t induce antibodies in some people and that antibody levels wane over time.<\/p>\n<p>If tens of millions of Africans have already been infected, that raises the question of whether the continent should try a \u201cherd immunity\u201d\u00a0 scenario without a vaccine, Boum says \u2014 the controversial idea of letting the virus run its course to allow the population to become immune, perhaps while shielding the most vulnerable.<\/p>\n<p>That might be preferable over control measures that cripple economies and could harm public health more in the long run.\u00a0\u201cMaybe Africa can afford it,\u201d given its apparent low death to infection ratio, Boum says.<\/p>\n<p>\u201cWe need to dig into that.\u201d\u00a0\u00a0But Glenda Gray, president of the South African Medical Research Council, says it could be dangerous to base Covid-19 policies on antibody surveys.<\/p>\n<p>It\u2019s not at all clear whether antibodies actually confer immunity, and if so, how long it lasts, Gray notes \u2014 in which case, she asks, \u201cWhat do these numbers really tell us?\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Author:\u00a0Linda Nordling\u00a0 AfricaPress-Kenya: Although Africa reported its millionth official Covid-19 case last week, it seems to have weathered the pandemic relatively well so far, with fewer than one confirmed case for every thousand people and just 23,000 deaths so far. Yet several antibody surveys suggest far more Africans have been infected with the coronavirus \u2014 [&hellip;]<\/p>\n","protected":false},"author":84,"featured_media":12773,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,2111,8,9],"tags":[4535,939,1539,2763],"class_list":["post-12780","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-all-news","category-coronavirus-in-kenya","category-homepage-english","category-miscellaneous","tag-africa","tag-coronavirus","tag-covid-19","tag-covid-19-pandemic"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.1 (Yoast SEO v27.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Scientists still puzzled by low corona deaths in Africa - kenya<\/title>\n<meta name=\"description\" content=\"Although Africa reported its millionth official Covid-19 case last week, it seems to have weathered the pandemic relatively well so far, with fewer than one\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/scientists-still-puzzled-by-low-corona-deaths-in-africa\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Scientists still puzzled by low corona deaths in Africa\" \/>\n<meta property=\"og:description\" content=\"Although Africa reported its millionth official Covid-19 case last week, it seems to have weathered the pandemic relatively well so far, with fewer than one\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/scientists-still-puzzled-by-low-corona-deaths-in-africa\" \/>\n<meta property=\"og:site_name\" content=\"kenya\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/AfricaPressTunisiaa\" \/>\n<meta property=\"article:published_time\" content=\"2020-08-14T14:43:32+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/static.africa-press.net\/kenya\/sites\/28\/2020\/08\/scientists_still_puz5f3576439d340.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"800\" \/>\n\t<meta property=\"og:image:height\" content=\"500\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"cfeditoren\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"cfeditoren\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/scientists-still-puzzled-by-low-corona-deaths-in-africa#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/scientists-still-puzzled-by-low-corona-deaths-in-africa\"},\"author\":{\"name\":\"cfeditoren\",\"@id\":\"https:\/\/www.africa-press.net\/kenya\/#\/schema\/person\/068c7ab4e9634ae78ec5d54ec46598bb\"},\"headline\":\"Scientists still puzzled by low corona deaths in Africa\",\"datePublished\":\"2020-08-14T14:43:32+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/scientists-still-puzzled-by-low-corona-deaths-in-africa\"},\"wordCount\":1024,\"commentCount\":0,\"image\":{\"@id\":\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/scientists-still-puzzled-by-low-corona-deaths-in-africa#primaryimage\"},\"thumbnailUrl\":\"https:\/\/static.africa-press.net\/kenya\/sites\/28\/2020\/08\/scientists_still_puz5f3576439d340.jpg\",\"keywords\":[\"Africa\",\"Coronavirus\",\"COVID-19\",\"Covid-19 pandemic\"],\"articleSection\":[\"all news\",\"Coronavirus in kenya\",\"homepage-english\",\"miscellaneous\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/scientists-still-puzzled-by-low-corona-deaths-in-africa#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/scientists-still-puzzled-by-low-corona-deaths-in-africa\",\"url\":\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/scientists-still-puzzled-by-low-corona-deaths-in-africa\",\"name\":\"Scientists still puzzled by low corona deaths in Africa - 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