{"id":17821,"date":"2020-11-19T21:06:29","date_gmt":"2020-11-19T21:06:29","guid":{"rendered":"https:\/\/www.africa-press.com\/kenya\/?p=17821"},"modified":"2020-11-19T21:06:29","modified_gmt":"2020-11-19T21:06:29","slug":"pfizer-biontech-vaccine-deliveries-could-start-before-christmas","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/pfizer-biontech-vaccine-deliveries-could-start-before-christmas","title":{"rendered":"Pfizer-BioNTech vaccine deliveries could start ‘before Christmas’"},"content":{"rendered":"

AfricaPress-Kenya:<\/strong> Pfizer Inc and BioNTech could secure emergency U.S. and European authorization for their COVID-19 vaccine next month after final trial results showed it had a 95% success rate and no serious side effects, the drugmakers said on Wednesday.<\/p>\n

The vaccine\u2019s efficacy was found to be consistent across different ages and ethnicities – a promising sign given the disease has disproportionately hurt the elderly and certain groups including Black people.<\/p>\n

The U.S. Food and Drug Administration could grant emergency-use by the middle of December, BioNTech Chief Executive Ugur Sahin told Reuters TV. Conditional approval in the European Union could be secured in the second half of December, he added.<\/p>\n

\u201cIf all goes well I could imagine that we gain approval in the second half of December and start deliveries before Christmas, but really only if all goes positively,\u201d he said.<\/p>\n

The success rate of the vaccine developed by the U.S. drugmaker and German partner BioNTech was far higher than what regulators had said would have been acceptable. Experts said it was a significant achievement in the race to end the pandemic.<\/p>\n

Of the 170 volunteers who contracted COVID-19 in Pfizer\u2019s trial involving over 43,000 people, 162 had received a placebo and not the vaccine, meaning the vaccine was 95% effective. Of the 10 people who had severe COVID-19, one had received the vaccine.<\/p>\n

\u201cA first in the history of mankind: less than a year from the sequence of the virus to the large-scale clinical trial of a vaccine, moreover based on a whole new technique,\u201d said Enrico Bucci, a biologist at Temple University in Philadelphia. \u201cToday is a special day.\u201d<\/p>\n

BioNTech\u2019s Sahin said U.S. emergency use authorization (EUA) would be applied for on Friday.<\/p>\n

An FDA advisory committee tentatively plans to meet on Dec. 8-10 to discuss the vaccine, a source familiar with the situation said, though the dates could change. The FDA did not respond to requests for comment.<\/p>\n

COVID-19 runs rampant<\/p>\n

The final trial analysis comes a week after initial results showed the vaccine was more than 90% effective. Moderna Inc on Monday released preliminary data for its vaccine showing 94.5% effectiveness.<\/p>\n

\u201cWe now have two safe and highly effective vaccines that could be authorized by the Food and Drug Administration and ready to distribute within weeks,\u201d U.S. Health and Human Services Secretary Alex Azar said.<\/p>\n

The Moderna vaccine is likely to be authorized within seven to 10 days of Pfizer receiving its EUA, U.S. officials said, with states ready to begin distribution within 24 hours.<\/p>\n

The better-than-expected results from the two vaccines, both developed with new messenger RNA (mRNA) technology, have raised hopes for an end to a pandemic that has killed more than 1.3 million people and wreaked havoc upon economies and daily life.<\/p>\n

The news was especially welcome with the virus again running rampant around the world, setting records for new infections and hospitalizations almost daily.<\/p>\n

The Pfizer-BioNTech shot was found to have 94% efficacy in people over age 65, a particularly high-risk group.<\/p>\n

\u201cThis is the evidence we needed to ensure that the most vulnerable people are protected,\u201d said Andrew Hill, senior visiting research fellow at the University of Liverpool\u2019s department of pharmacology.<\/p>\n

Global shares rose as the trial results countered concerns around the soaring infection rate. Pfizer shares were up 1.6% while BioNTech jumped 3.8% in the United States. Moderna shares fell 3.6%.<\/p>\n

Investors have treated vaccine development as a race between companies, although there is likely to be global demand for as much vaccine as can be produced for the foreseeable future.<\/p>\n

Distributing shots<\/p>\n

Pfizer said it expects to make as many as 50 million vaccine doses this year, enough to protect 25 million people, and then produce up to 1.3 billion doses in 2021.<\/p>\n

While some groups such as healthcare workers will be prioritized in the United States and Britain for vaccinations, it will be months before large-scale rollouts begin in either country.<\/p>\n

On Wednesday, Pfizer said it had offered to provide Brazil with millions of doses in the first half of 2021. It also has agreements with the European Union, Germany and Japan where distribution could begin next year.<\/p>\n

Mike Ryan, the World Health Organization\u2019s top emergency expert, said it would be at least 4-6 months before significant levels of vaccination were taking place around the world.<\/p>\n

Distribution of a Pfizer-BioNTech shot is complicated by the need to store it at ultra-cold temperatures of -70 degrees Celsius. It can, however, be kept in normal refrigeration for up to five days, or up to 15 days in a thermal shipping box.<\/p>\n

Moderna\u2019s vaccine can be stored for up to six months at -20C though it is expected to be stable for 30 days at normal fridge temperatures of 2 to 8 degrees Celsius (36\u00b0-46\u00b0F).<\/p>\n

Fatigue and headaches<\/p>\n

Pfizer said vaccine was well-tolerated and that side effects were mostly mild to moderate, and cleared up quickly. The only severe adverse events experienced by volunteers were fatigue (3.8%) and headaches (2%) after the second dose. Older adults tended to report fewer and milder adverse events.<\/p>\n

\u201cThese are extraordinary results, and the safety data look good,\u201d said David Spiegelhalter, a professor and expert in risk and evidence communication at the University of Cambridge.<\/p>\n

Of the dozens of drugmakers and research groups racing to develop COVID-19 vaccines, the next late-stage data will likely be from AstraZeneca Plc with the University of Oxford in November or December. Johnson & Johnson said it is on track to deliver data this year.<\/p>\n

Authorization of vaccines for children will take longer. Only Pfizer has started vaccinating volunteers under age 18 and as young as 12. Moderna and J&J have said they hope to start testing the vaccine in younger people soon.<\/p>\n","protected":false},"excerpt":{"rendered":"

AfricaPress-Kenya: Pfizer Inc and BioNTech could secure emergency U.S. and European authorization for their COVID-19 vaccine next month after final trial results showed it had a 95% success rate and no serious side effects, the drugmakers said on Wednesday. The vaccine\u2019s efficacy was found to be consistent across different ages and ethnicities – a promising […]<\/p>\n","protected":false},"author":84,"featured_media":17822,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,8,9],"tags":[3215,1539,6441],"class_list":["post-17821","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-all-news","category-homepage-english","category-miscellaneous","tag-coronavirus-vaccine","tag-covid-19","tag-pfizer"],"yoast_head":"\nPfizer-BioNTech vaccine deliveries could start 'before Christmas' - kenya<\/title>\n<meta name=\"description\" content=\"Pfizer Inc and BioNTech could secure emergency U.S. and European authorization for their COVID-19 vaccine next month after final trial\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/pfizer-biontech-vaccine-deliveries-could-start-before-christmas\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pfizer-BioNTech vaccine deliveries could start 'before Christmas'\" \/>\n<meta property=\"og:description\" content=\"Pfizer Inc and BioNTech could secure emergency U.S. and European authorization for their COVID-19 vaccine next month after final trial\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/pfizer-biontech-vaccine-deliveries-could-start-before-christmas\" \/>\n<meta property=\"og:site_name\" content=\"kenya\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/AfricaPressTunisiaa\" \/>\n<meta property=\"article:published_time\" content=\"2020-11-19T21:06:29+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/static.africa-press.net\/kenya\/sites\/28\/2020\/11\/ypcrvkboribazwlu5fb5ed1f711c2.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"800\" \/>\n\t<meta property=\"og:image:height\" content=\"586\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"cfeditoren\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"cfeditoren\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/pfizer-biontech-vaccine-deliveries-could-start-before-christmas#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/pfizer-biontech-vaccine-deliveries-could-start-before-christmas\"},\"author\":{\"name\":\"cfeditoren\",\"@id\":\"https:\/\/www.africa-press.net\/kenya\/#\/schema\/person\/068c7ab4e9634ae78ec5d54ec46598bb\"},\"headline\":\"Pfizer-BioNTech vaccine deliveries could start ‘before Christmas’\",\"datePublished\":\"2020-11-19T21:06:29+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/pfizer-biontech-vaccine-deliveries-could-start-before-christmas\"},\"wordCount\":946,\"commentCount\":0,\"image\":{\"@id\":\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/pfizer-biontech-vaccine-deliveries-could-start-before-christmas#primaryimage\"},\"thumbnailUrl\":\"https:\/\/static.africa-press.net\/kenya\/sites\/28\/2020\/11\/ypcrvkboribazwlu5fb5ed1f711c2.jpg\",\"keywords\":[\"Coronavirus Vaccine\",\"COVID-19\",\"Pfizer\"],\"articleSection\":[\"all news\",\"homepage-english\",\"miscellaneous\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/pfizer-biontech-vaccine-deliveries-could-start-before-christmas#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/pfizer-biontech-vaccine-deliveries-could-start-before-christmas\",\"url\":\"https:\/\/www.africa-press.net\/kenya\/miscellaneous\/pfizer-biontech-vaccine-deliveries-could-start-before-christmas\",\"name\":\"Pfizer-BioNTech vaccine deliveries could start 'before Christmas' - 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