{"id":16993,"date":"2023-08-04T19:59:58","date_gmt":"2023-08-04T19:59:58","guid":{"rendered":"https:\/\/www.africa-press.net\/madagascar\/politique\/une-etude-montre-quil-ne-faut-plus-prescrire-de-laspirine-en-prevention-des-avc"},"modified":"2023-08-04T21:35:13","modified_gmt":"2023-08-04T21:35:13","slug":"une-etude-montre-quil-ne-faut-plus-prescrire-de-laspirine-en-prevention-des-avc","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/madagascar\/toutes-les-actualites\/une-etude-montre-quil-ne-faut-plus-prescrire-de-laspirine-en-prevention-des-avc","title":{"rendered":"Une \u00e9tude montre qu\u2019il ne faut plus prescrire de l\u2019aspirine en pr\u00e9vention des AVC"},"content":{"rendered":"

Africa-Press – Madagascar. <\/strong><\/span>Prescrire une faible dose d\u2019aspirine a\u0300 prendre quotidiennement est une pratique re\u0301pandue chez les me\u0301decins pour pre\u0301venir le risque d\u2019accident vasculaire ce\u0301re\u0301bral (AVC). Et si ce traitement pre\u0301ventif pre\u0301sentait finalement plus de risques que d\u2019avantages, en particulier chez les personnes a\u0302ge\u0301es ? Lance\u0301 en 2010 en Australie, le projet ASPREE est ne\u0301 d\u2019une pre\u0301occupation des chercheurs a\u0300 propos de la fre\u0301quence tre\u0300s e\u0301leve\u0301e de l\u2019utilisation de l\u2019aspirine a\u0300 faible dose chez des personnes en bonne sante\u0301. En 2018, trois articles ont e\u0301te\u0301 publie\u0301s, de\u0301montrant que l\u2019aspirine n\u2019apportait aucun be\u0301ne\u0301fice dans le cadre de la pre\u0301vention des AVC. Certains que les risques e\u0301taient e\u0301leve\u0301s, en particulier pour les personnes a\u0302ge\u0301es, et sachant cette pratique bien ancre\u0301e, les chercheurs ont poursuivi leurs recherches. Ils publient ce mois-ci dans JAMA Open Network leurs derniers re\u0301sultats, examinant l\u2019impact de l\u2019aspirine a\u0300 faible dose sur les accidents vasculaires ce\u0301re\u0301braux et les he\u0301morragies intracra\u0302niennes (he\u0301morragies a\u0300 l\u2019inte\u0301rieur du tissu ce\u0301re\u0301bral).<\/p>\n

\u201cPour ce groupe d\u2019a\u0302ge, la prise quotidienne d\u2019aspirine augmente le risque he\u0301morragique\u201d<\/b><\/p>\n

Malgre\u0301 l\u2019e\u0301mergence d\u2019e\u0301tudes contre la prise quotidienne d\u2019aspirine, me\u0302me a\u0300 faible dose, de nombreux me\u0301decins continuent de de\u0301livrer cette prescription aux personnes a\u0302ge\u0301es, souvent en \u201cpre\u0301vention secondaire\u201d pour e\u0301viter un deuxie\u0300me AVC. \u201cPour ce groupe d\u2019a\u0302ge, la prise quotidienne d\u2019aspirine augmente le risque he\u0301morragique\u201d, alerte John McNeil, professeur a\u0300 l\u2019universite\u0301 Monash en Australie, et co-auteur de l\u2019e\u0301tude.<\/p>\n

L\u2019essai mene\u0301 dans le cadre du projet ASPREE sur pre\u0300s de 19.000 personnes a\u0302ge\u0301es (en moyenne 74 ans) a en effet montre\u0301 une augmentation statistiquement significative de 38 % des saignements intracra\u0302niens chez les patients qui prenaient quotidiennement 100 mg d\u2019aspirine. \u201cL\u2019aspirine bloque de manie\u0300re irre\u0301versible la contribution des plaquettes a\u0300 la coagulation du sang, et cette fonction ne se re\u0301tablit que lorsque de nouvelles plaquettes sont libe\u0301re\u0301es de la moelle osseuse, soit tous les 10 a\u0300 12 jours\u201d, explique le professeur McNeil.<\/p>\n

Des saignements qui ne concernent pas uniquement le cerveau<\/b><\/p>\n

En prescrivant de l\u2019aspirine, les me\u0301decins espe\u0300rent fluidifier le sang et e\u0301viter la formation de caillots qui pourraient se de\u0301tacher et bloquer brutalement le flux sanguin ce\u0301re\u0301bral, entrainant un AVC. Mais chez les personnes a\u0302ge\u0301es, les risques sont plus bien plus grands que les avantages. \u201cLes he\u0301morragies intra-ce\u0301re\u0301brales arrivent plus fre\u0301quemment chez les personnes a\u0302ge\u0301es parce que leurs vaisseaux sanguins sont plus fragiles, et l\u2019aspirine entrave le me\u0301canisme de coagulation qui arre\u0302te l\u2019he\u0301morragie\u201d, poursuit le professeur. Ces saignements ne concernent pas seulement le cerveau, et peuvent intervenir dans tout le corps, en particulier chez des personnes a\u0302ge\u0301es sujettes aux chutes. Le cumul des risques he\u0301morragiques annule donc l\u2019e\u0301ventuel be\u0301ne\u0301fice que pourrait apporter une pre\u0301vention secondaire, surtout lorsque celle-ci a e\u0301te\u0301 de\u0301montre\u0301e inefficace.<\/p>\n

\u201cUn bon contro\u0302le de la tension arte\u0301rielle et l\u2019administration de statines (traitement contre le choleste\u0301rol) pour re\u0301duire les concentrations de lipides dans le plasma sont des e\u0301le\u0301ments cle\u0301s de la pre\u0301vention des AVC\u201d, assure John McNeil, dont l\u2019e\u0301quipe poursuit les recherches sur les effets de l\u2019aspirine.<\/p>\n

Pour plus d’informations et d’analyses sur la Madagascar<\/a>, suivez Africa-Press<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Africa-Press – Madagascar. Prescrire une faible dose d\u2019aspirine a\u0300 prendre quotidiennement est une pratique re\u0301pandue chez les me\u0301decins pour pre\u0301venir le risque d\u2019accident vasculaire ce\u0301re\u0301bral (AVC). Et si ce traitement pre\u0301ventif pre\u0301sentait finalement plus de risques que d\u2019avantages, en particulier chez les personnes a\u0302ge\u0301es ? Lance\u0301 en 2010 en Australie, le projet ASPREE est ne\u0301 […]<\/p>\n","protected":false},"author":82,"featured_media":16991,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[22,10],"tags":[36,50,49],"class_list":["post-16993","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divers","category-toutes-les-actualites","tag-africa-press","tag-africa-press-madagascar","tag-madagascar"],"yoast_head":"\nUne \u00e9tude montre qu\u2019il ne faut plus prescrire de l\u2019aspirine en pr\u00e9vention des AVC - Madagascar<\/title>\n<meta name=\"description\" content=\"Prescrire une faible dose d\u2019aspirine a\u0300 prendre quotidiennement est une pratique re\u0301pandue chez les me\u0301decins pour pre\u0301v ...\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.africa-press.net\/madagascar\/toutes-les-actualites\/une-etude-montre-quil-ne-faut-plus-prescrire-de-laspirine-en-prevention-des-avc\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Une \u00e9tude montre qu\u2019il ne faut plus prescrire de l\u2019aspirine en pr\u00e9vention des AVC\" \/>\n<meta property=\"og:description\" content=\"Prescrire une faible dose d\u2019aspirine a\u0300 prendre quotidiennement est une pratique re\u0301pandue chez les me\u0301decins pour pre\u0301v ...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.africa-press.net\/madagascar\/toutes-les-actualites\/une-etude-montre-quil-ne-faut-plus-prescrire-de-laspirine-en-prevention-des-avc\" \/>\n<meta property=\"og:site_name\" content=\"Madagascar\" \/>\n<meta property=\"article:published_time\" content=\"2023-08-04T19:59:58+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-08-04T21:35:13+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/static.africa-press.net\/madagascar\/sites\/56\/2023\/08\/sm_1691168306.251622.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"898\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"cfeditorfr\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"cfeditorfr\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.africa-press.net\/madagascar\/toutes-les-actualites\/une-etude-montre-quil-ne-faut-plus-prescrire-de-laspirine-en-prevention-des-avc#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.africa-press.net\/madagascar\/toutes-les-actualites\/une-etude-montre-quil-ne-faut-plus-prescrire-de-laspirine-en-prevention-des-avc\"},\"author\":{\"name\":\"cfeditorfr\",\"@id\":\"https:\/\/www.africa-press.net\/madagascar\/#\/schema\/person\/2b1cf3cd81a31e3cd26889ca66d677f1\"},\"headline\":\"Une \u00e9tude montre qu\u2019il ne faut plus prescrire de l\u2019aspirine en pr\u00e9vention des AVC\",\"datePublished\":\"2023-08-04T19:59:58+00:00\",\"dateModified\":\"2023-08-04T21:35:13+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.africa-press.net\/madagascar\/toutes-les-actualites\/une-etude-montre-quil-ne-faut-plus-prescrire-de-laspirine-en-prevention-des-avc\"},\"wordCount\":630,\"commentCount\":0,\"image\":{\"@id\":\"https:\/\/www.africa-press.net\/madagascar\/toutes-les-actualites\/une-etude-montre-quil-ne-faut-plus-prescrire-de-laspirine-en-prevention-des-avc#primaryimage\"},\"thumbnailUrl\":\"https:\/\/static.africa-press.net\/madagascar\/sites\/56\/2023\/08\/sm_1691168306.251622.jpg\",\"keywords\":[\"Africa Press\",\"Africa Press-Madagascar\",\"Madagascar\"],\"articleSection\":[\"Divers\",\"Toutes les actualit\u00e9s\"],\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.africa-press.net\/madagascar\/toutes-les-actualites\/une-etude-montre-quil-ne-faut-plus-prescrire-de-laspirine-en-prevention-des-avc#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.africa-press.net\/madagascar\/toutes-les-actualites\/une-etude-montre-quil-ne-faut-plus-prescrire-de-laspirine-en-prevention-des-avc\",\"url\":\"https:\/\/www.africa-press.net\/madagascar\/toutes-les-actualites\/une-etude-montre-quil-ne-faut-plus-prescrire-de-laspirine-en-prevention-des-avc\",\"name\":\"Une \u00e9tude montre qu\u2019il ne faut plus prescrire de l\u2019aspirine en pr\u00e9vention des AVC - 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