{"id":20028,"date":"2023-10-09T19:40:11","date_gmt":"2023-10-09T19:40:11","guid":{"rendered":"https:\/\/www.africa-press.net\/madagascar\/politique\/des-medicaments-contre-lobesite-augmentent-le-risque-de-problemes-gastro-intestinaux"},"modified":"2023-10-09T21:24:16","modified_gmt":"2023-10-09T21:24:16","slug":"des-medicaments-contre-lobesite-augmentent-le-risque-de-problemes-gastro-intestinaux","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/madagascar\/toutes-les-actualites\/des-medicaments-contre-lobesite-augmentent-le-risque-de-problemes-gastro-intestinaux","title":{"rendered":"Des m\u00e9dicaments contre l\u2019ob\u00e9sit\u00e9 augmentent le risque de probl\u00e8mes gastro-intestinaux"},"content":{"rendered":"

Africa-Press – Madagascar. <\/strong><\/span>Les experts soulignent que ces re\u0301sultats montrent la ne\u0301cessite\u0301 de prescrire ces me\u0301dicaments a\u0300 des patients qui en tirent un re\u0301el be\u0301ne\u0301fice, informe\u0301s des risques, et suivis par des professionnels de sante\u0301.<\/p>\n

Des me\u0301dicaments devenus tre\u0300s populaires pour perdre du poids, comme Ozempic, augmentent le risque de proble\u0300mes gastro-intestinaux, ont alerte\u0301 des chercheurs dans une e\u0301tude publie\u0301e le 5 octobre 2023.<\/p>\n

Des centaines de milliers de personnes potentiellement concerne\u0301es<\/b><\/p>\n

Ces effets secondaires restent rares, et doivent e\u0302tre compare\u0301s aux proble\u0300mes de sante\u0301 lie\u0301s a\u0300 l\u2019obe\u0301site\u0301 qui peuvent e\u0302tre e\u0301vite\u0301s gra\u0302ce a\u0300 une perte de poids. Mais les experts soulignent que ces re\u0301sultats montrent la ne\u0301cessite\u0301 de prescrire ces me\u0301dicaments a\u0300 des patients qui en tirent un re\u0301el be\u0301ne\u0301fice, informe\u0301s des risques, et suivis par des professionnels de sante\u0301.<\/p>\n

\u201cAvec des millions de personnes prenant ces me\u0301dicaments dans le monde, cela pourrait conduire des centaines de milliers de personnes souffrant de ces proble\u0300mes\u201d, a souligne\u0301 un communique\u0301 l\u2019Universite\u0301 de la Colombie-Britannique (Canada), dont les chercheurs ont re\u0301alise\u0301 l\u2019e\u0301tude.<\/p>\n

Pancre\u0301atite, gastropare\u0301sie et occlusion intestinale<\/b><\/p>\n

Les chercheurs se sont penche\u0301s sur la mole\u0301cule semaglutide, utilise\u0301e dans les me\u0301dicaments a\u0300 succe\u0300s Ozempic et Wegovy, ainsi que la liraglutide, du me\u0301dicament Saxenda. Tous sont produits par le laboratoire Novo Nordisk. Ces nouveaux traitements par injection, devenus populaires car plus efficaces pour perdre du poids que ceux d\u2019ancienne ge\u0301ne\u0301ration, imitent une hormone gastro-intestinale (GLP-1) qui joue un ro\u0302le dans la re\u0301gulation de l\u2019appe\u0301tit.<\/p>\n

Les chercheurs ont inclus dans leur analyse environ 5.400 patients obe\u0300ses sans diabe\u0300te, et ont compare\u0301 ceux prenant semaglutide ou liraglutide, avec ceux prenant un autre traitement contre l\u2019obe\u0301site\u0301 (non GLP-1). Selon leurs re\u0301sultats, les patients traite\u0301s avec semaglutide ou liraglutide avaient environ 9 fois plus de risque de de\u0301velopper une pancre\u0301atite (inflammation du pancre\u0301as), et plus de 4 fois plus de risque de de\u0301velopper une occlusion intestinale.<\/p>\n

Pour la gastropare\u0301sie, trouble digestif limitant le passage de la nourriture et pouvant entrai\u0302ner nause\u0301e, vomissements et douleurs, le risque e\u0301tait plus de 3 fois plus e\u0301leve\u0301.<\/p>\n

Des re\u0300glementations attendues<\/b><\/p>\n

Ces me\u0301dicaments \u201cdevraient e\u0302tre utilise\u0301s avec pre\u0301caution, et seulement chez les patients avec le plus haut risque de proble\u0300mes de sante\u0301 ou de complications lie\u0301s a\u0300 l\u2019obe\u0301site\u0301\u201d, a commente\u0301 la professeure en me\u0301decine pharmaceutique Penny Ward, non implique\u0301e dans l\u2019e\u0301tude. \u201cIl est vital que les re\u0301glementations soient renforce\u0301es pour s\u2019assurer que ces me\u0301dicaments ne soient prescrits que dans les bonnes circonstances\u201d, a de son co\u0302te\u0301 estime\u0301 le Dr. Simon Cork, de l\u2019Universite\u0301 Anglia Ruskin, jugeant les donne\u0301es de l\u2019e\u0301tude \u201cfiables\u201d.<\/p>\n

Aux Etats-Unis, Ozempic n\u2019est approuve\u0301 que contre le diabe\u0300te, mais apre\u0300s avoir fait fureur sur les re\u0301seaux sociaux, il est aussi largement utilise\u0301 hors des recommandations, pour ses proprie\u0301te\u0301s amaigrissantes. Saxenda et Wegovy sont eux approuve\u0301s par les autorite\u0301s sanitaires ame\u0301ricaines pour la perte de poids, depuis 2020 et 2021 respectivement.<\/p>\n

Mais les essais cliniques re\u0301alise\u0301s pour leur autorisation e\u0301taient trop petits et brefs pour de\u0301tecter ces risques gastro-intestinaux, selon les chercheurs de l\u2019Universite\u0301 de la Colombie-Britannique, qui arguent qu\u2019il s\u2019agit de la premie\u0300re e\u0301tude d\u2019ampleur sur le sujet.<\/p>\n

Pour plus d’informations et d’analyses sur la Madagascar<\/a>, suivez Africa-Press<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Africa-Press – Madagascar. Les experts soulignent que ces re\u0301sultats montrent la ne\u0301cessite\u0301 de prescrire ces me\u0301dicaments a\u0300 des patients qui en tirent un re\u0301el be\u0301ne\u0301fice, informe\u0301s des risques, et suivis par des professionnels de sante\u0301. Des me\u0301dicaments devenus tre\u0300s populaires pour perdre du poids, comme Ozempic, augmentent le risque de proble\u0300mes gastro-intestinaux, ont alerte\u0301 des […]<\/p>\n","protected":false},"author":82,"featured_media":20027,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[22,10],"tags":[36,50,49],"class_list":["post-20028","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divers","category-toutes-les-actualites","tag-africa-press","tag-africa-press-madagascar","tag-madagascar"],"yoast_head":"\nDes m\u00e9dicaments contre l\u2019ob\u00e9sit\u00e9 augmentent le risque de probl\u00e8mes gastro-intestinaux - Madagascar<\/title>\n<meta name=\"description\" content=\"Les experts soulignent que ces re\u0301sultats montrent la ne\u0301cessite\u0301 de prescrire ces me\u0301dicaments a\u0300 des patients qui en t ...\" \/>\n<meta name=\"robots\" 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