{"id":2840,"date":"2021-07-21T15:28:27","date_gmt":"2021-07-21T15:28:27","guid":{"rendered":"https:\/\/www.africa-press.net\/mozambique\/?p=2840"},"modified":"2021-07-21T15:43:44","modified_gmt":"2021-07-21T15:43:44","slug":"mozambique-country-to-host-ecova-clinical-trials-of-sinopharm-covid-19-vaccine","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/mozambique\/all-news\/mozambique-country-to-host-ecova-clinical-trials-of-sinopharm-covid-19-vaccine","title":{"rendered":"Country to host ECOVA clinical trials of Sinopharm Covid-19 vaccine"},"content":{"rendered":"

Africa-Press<\/a> – Mozambique<\/a>. <\/strong><\/span>Mozambique is to host two clinical trials of China\u2019s Sinopharm vaccine as part of the ECOVA initiative to expand the distribution of vaccines against Covid-19 in Africa, in an effort to assess their effectiveness against new variants of the coronavirus that causes the disease.<\/p>\n

The clinical trials, which are to begin soon in Maputo and Beira, the country\u2019s second city, are to be led by Mozambique\u2019s National Institute of Health (INS) in collaboration with the International Vaccine Institute (IVI), according to a statement from the The Coalition for Epidemic Preparedness Innovations (CEPI).<\/p>\n

The first interim results are expected before the end of this year and participants in the trials are to be monitored for two years to gather important long-term data on the vaccine, it adds.<\/p>\n

Ina Phase 3 strial, \u201cthe safety and efficacy of BBIBP-CorV against locally circulating variants of concern (VoCs) in healthy adults\u201d will be assessed, the statement says, giving the scientific name of the vaccine.<\/p>\n

\u201d This will be the first trial of this vaccine in an African population, and against the VoCs prevalent in much of southern Africa,\u201d it goes on. \u201d The trial will also assess the vaccine\u2019s safety and immunogenicity in HIV-infected individuals, which could broaden the indication of the vaccine for use in this population. In addition, it will investigate the potential for co-administration of BBIBP-CorV with seasonal influenza vaccines\u201d.<\/p>\n

A separate Phase 2 mix and match trial will, meanwhile, \u201cevaluate the safety and immunogenicity of mixed schedules of BBIBP-CorV and AstraZeneca\u2019s COVID-19 vaccine \u201d \u2013 which, as CEPI notes, are both likely to feature significantly in Africa\u2019s vaccine rollout, which could bring greater flexibility to vaccination campaigns at times of uncertain or fluctuating supplies..\u201d<\/p>\n

According to the news release, this new clinical trials programme aims to expand access to Covid-19 vaccines in Africa.<\/p>\n

\u201cCEPI will provide funding of up to $12.7m to the Expanding Access and Delivery of COVID-19 Vaccines in Africa (ECOVA) consortium led by IVI to carry out clinical trials of Sinopharm\u2019s BBIBP-CorV vaccine ,,\u201d it stresses.<\/p>\n

Up to 170 million doses of BBIBP-CorV are to be distributed, according to an agreement announced on 12 July, with the vaccine already being administered in more than 50 countries worldwide.<\/p>\n

\u201cHowever there have been no clinical trials of BBIBP-CorV in African populations or against the variants of concern circulating in southern Africa,\u201d the statement explains. \u201d All results generated by ECOVA will be made available open source to inform policy makers and regulatory authorities\u2019 recommendations on the use of BBIBP-CorV in national immunisation programmes\u201d.<\/p>\n

Richard Hatchett, CEO of CEP, is also quoted in the statement.<\/p>\n

\u201cOnly a handful of clinical trials of COVID-19 vaccines have taken place in sub-Saharan Africa,\u201d he says. \u201cBut for vaccines to have the maximum impact they must be evaluated in the populations that will receive them and against the variants those populations are most likely to encounter\u201d.<\/p>\n

The director-general of Mozambique\u2019s National Institute of Immunology (INS), Ilesh V. Jani, stressed that this is an \u201cimportant study to evaluate the efficacy of COVID-19 vaccines against new variants of concern\u2013particularly the Beta and Delta variants which now account for the majority of infections in our region\u201d.<\/p>\n

The ECOVA consortium is led by the International Vaccine Institute, working in partnership with Mozambique\u2019s Instituto Nacional de Sa\u00fade (INS), the International Centre for Diarrhoeal Disease Research, Bangladesh, the University of Heidelberg, Germany, Harvard University, USA, and the University of Antananarivo, in Madagascar.<\/p>\n

ECOVA is the second programme to be funded with a focus on addressing current gaps in scientific knowledge about vaccine performance, in the short and long term, to expand access to Covid-19 vaccines as part of the global immunisation effort.<\/p>\n

Among gaps already identified are the safety and efficacy of the vaccines in pregnant women, infants and children and immunodepressed populations, as well as studies on booster doses, duration of vaccine efficacy, vaccine type combination strategies or dosing intervals.<\/p>\n

We\u2019re pleased to announce a new clinical research program with @CEPIvaccines aiming to expand access to COVID-19 vaccines in Africa ?<\/p>\n

Learn more about ECOVA, led by IVI with @instituto_ins @icddr_b @UniHeidelberg @Harvard & University of Antananarivo ? https:\/\/t.co\/feyFnruYqa<\/p>\n

\u2014 International Vaccine Institute (IVI) (@IVIHeadquarters) July 20, 2021<\/p>\n","protected":false},"excerpt":{"rendered":"

Africa-Press – Mozambique. Mozambique is to host two clinical trials of China\u2019s Sinopharm vaccine as part of the ECOVA initiative to expand the distribution of vaccines against Covid-19 in Africa, in an effort to assess their effectiveness against new variants of the coronavirus that causes the disease. The clinical trials, which are to begin soon […]<\/p>\n","protected":false},"author":84,"featured_media":2839,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,3,8,16],"tags":[233,281,283],"class_list":["post-2840","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-all-news","category-community","category-homepage-english","category-twitter","tag-africa-press","tag-africa-press-mozambique","tag-mozambique"],"yoast_head":"\nCountry to host ECOVA clinical trials of Sinopharm Covid-19 vaccine - Mozambique<\/title>\n<meta name=\"description\" content=\"Mozambique is to host two clinical trials of China\u2019s Sinopharm vaccine as part of the ECOVA initiative to expand the dis ...\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.africa-press.net\/mozambique\/all-news\/mozambique-country-to-host-ecova-clinical-trials-of-sinopharm-covid-19-vaccine\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Country to host ECOVA clinical trials of Sinopharm Covid-19 vaccine\" \/>\n<meta property=\"og:description\" content=\"Mozambique is to host two clinical trials of China\u2019s Sinopharm vaccine as part of the ECOVA initiative to expand the dis ...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.africa-press.net\/mozambique\/all-news\/mozambique-country-to-host-ecova-clinical-trials-of-sinopharm-covid-19-vaccine\" \/>\n<meta property=\"og:site_name\" content=\"Mozambique\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/AfricaPressTunisiaa\" \/>\n<meta property=\"article:published_time\" content=\"2021-07-21T15:28:27+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-07-21T15:43:44+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/static.africa-press.net\/mozambique\/sites\/64\/2021\/07\/img-60f83951103ed.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"730\" \/>\n\t<meta property=\"og:image:height\" content=\"438\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"cfeditoren\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"cfeditoren\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.africa-press.net\/mozambique\/all-news\/mozambique-country-to-host-ecova-clinical-trials-of-sinopharm-covid-19-vaccine#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.africa-press.net\/mozambique\/all-news\/mozambique-country-to-host-ecova-clinical-trials-of-sinopharm-covid-19-vaccine\"},\"author\":{\"name\":\"cfeditoren\",\"@id\":\"https:\/\/www.africa-press.net\/mozambique\/#\/schema\/person\/068c7ab4e9634ae78ec5d54ec46598bb\"},\"headline\":\"Country to host ECOVA clinical trials of Sinopharm Covid-19 vaccine\",\"datePublished\":\"2021-07-21T15:28:27+00:00\",\"dateModified\":\"2021-07-21T15:43:44+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.africa-press.net\/mozambique\/all-news\/mozambique-country-to-host-ecova-clinical-trials-of-sinopharm-covid-19-vaccine\"},\"wordCount\":712,\"commentCount\":0,\"image\":{\"@id\":\"https:\/\/www.africa-press.net\/mozambique\/all-news\/mozambique-country-to-host-ecova-clinical-trials-of-sinopharm-covid-19-vaccine#primaryimage\"},\"thumbnailUrl\":\"https:\/\/static.africa-press.net\/mozambique\/sites\/64\/2021\/07\/img-60f83951103ed.jpg\",\"keywords\":[\"Africa Press\",\"Africa Press-Mozambique\",\"Mozambique\"],\"articleSection\":[\"all news\",\"community\",\"homepage-english\",\"twitter\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.africa-press.net\/mozambique\/all-news\/mozambique-country-to-host-ecova-clinical-trials-of-sinopharm-covid-19-vaccine#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.africa-press.net\/mozambique\/all-news\/mozambique-country-to-host-ecova-clinical-trials-of-sinopharm-covid-19-vaccine\",\"url\":\"https:\/\/www.africa-press.net\/mozambique\/all-news\/mozambique-country-to-host-ecova-clinical-trials-of-sinopharm-covid-19-vaccine\",\"name\":\"Country to host ECOVA clinical trials of Sinopharm Covid-19 vaccine - 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