{"id":2457,"date":"2021-01-27T18:08:18","date_gmt":"2021-01-27T18:08:18","guid":{"rendered":"https:\/\/www.africa-press.net\/niger\/?p=2457"},"modified":"2021-01-27T18:07:36","modified_gmt":"2021-01-27T18:07:36","slug":"covid-19-la-colchicine-reduit-le-risque-de-complications-etude-colcorona","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/niger\/toutes-les-actualites\/covid-19-la-colchicine-reduit-le-risque-de-complications-etude-colcorona","title":{"rendered":"COVID-19 : La colchicine r\u00e9duit le risque de complications (Etude COLCORONA)"},"content":{"rendered":"

Africa-Press<\/a> – Niger<\/a>. <\/strong><\/span>Les r\u00e9sultats de l\u2019\u00e9tude \u201cCOLCORONA\u201d ont montr\u00e9 que la colchicine est le seul m\u00e9dicament oral efficace pour traiter les patients non-hospitalis\u00e9s du COVID-19.<\/p>\n

L\u2019Institut de Cardiologie de Montr\u00e9al (ICM) a annonc\u00e9 le 22 janvier 2021 que l\u2019\u00e9tude COLCORONA a fourni des r\u00e9sultats cliniquement convaincants de l\u2019efficacit\u00e9 de la colchicine (alcalo\u00efde ou mol\u00e9cule tricyclique toxique) pour traiter le COVID-19.<\/p>\n

COLCORONA est une \u00e9tude clinique \u00ab sans contact \u00bb qui s\u2019est d\u00e9roul\u00e9e \u00e0 la maison, randomis\u00e9e, \u00e0 double insu et contr\u00f4l\u00e9e par plac\u00e9bo. Elle a \u00e9t\u00e9 d\u00e9ploy\u00e9e au Canada, aux \u00c9tats-Unis, en Europe, en Am\u00e9rique du Sud ainsi qu\u2019en Afrique du Sud. Elle visait \u00e0 d\u00e9terminer si la colchicine pouvait r\u00e9duire les risques de complications s\u00e9v\u00e8res li\u00e9es au COVID-19.<\/p>\n

COLCORONA a \u00e9t\u00e9 men\u00e9e aupr\u00e8s d\u2019environ 4\u2009500 patients atteints du COVID-19 n\u2019\u00e9tant pas hospitalis\u00e9s au moment de l\u2019inclusion, avec au moins un facteur de risque de complications. Il s\u2019agit de la plus grande \u00e9tude \u00e0 l\u2019\u00e9chelle mondiale testant un m\u00e9dicament administr\u00e9 oralement chez les patients non-hospitalis\u00e9s.<\/p>\n

Les r\u00e9sultats de l\u2019\u00e9tude ont d\u00e9montr\u00e9 que la colchicine a r\u00e9duit de 21% le risque de d\u00e9c\u00e8s ou d\u2019hospitalisations chez les patients atteints de COVID-19 comparativement au plac\u00e9bo. Ce r\u00e9sultat obtenu pour l\u2019ensemble des 4 488 patients de l\u2019\u00e9tude approchait la signification statistique.<\/p>\n

L\u2019analyse de 4 159 patients dont le diagnostic de COVID-19 \u00e9tait prouv\u00e9 par un test naso-pharyng\u00e9 (PCR) a montr\u00e9 que la colchicine r\u00e9duisait de fa\u00e7on statistiquement significative le risque de d\u00e9c\u00e8s ou d\u2019hospitalisations comparativement au plac\u00e9bo.<\/p>\n

Chez ces patients avec diagnostic prouv\u00e9 de COVID-19, la colchicine a entra\u00een\u00e9 des r\u00e9ductions des hospitalisations de 25%, du besoin de ventilation m\u00e9canique de 50%, et des d\u00e9c\u00e8s de 44%. Cette d\u00e9couverte scientifique majeure fait de la colchicine le premier m\u00e9dicament oral au monde qui pourrait traiter les patients en phase pr\u00e9-hospitali\u00e8re.<\/p>\n

\u00ab\u2009Notre \u00e9tude a montr\u00e9 l\u2019efficacit\u00e9 du traitement utilisant la colchicine pour pr\u00e9venir le ph\u00e9nom\u00e8ne de \u00ab temp\u00eate inflammatoire majeure \u00bb et pour r\u00e9duire les complications li\u00e9es au COVID-19\u2009\u00bb, a d\u00e9clar\u00e9 le Dr Jean-Claude Tardif, directeur du Centre de recherche de l\u2019ICM, professeur de m\u00e9decine \u00e0 l\u2019Universit\u00e9 de Montr\u00e9al et chercheur principal de l\u2019\u00e9tude COLCORONA.<\/p>\n

Traiter les patients \u00e0 risque de complications avec la colchicine d\u00e8s la confirmation du diagnostic de COVID-19 par PCR permet de r\u00e9duire leur risque de d\u00e9velopper une forme grave de la maladie et cons\u00e9quemment diminuer le nombre d\u2019hospitalisations, a-t-il ajout\u00e9.<\/p>\n

\u00ab\u2009Nous sommes heureux d\u2019offrir le premier m\u00e9dicament oral au monde dont l\u2019utilisation pourrait avoir une incidence importante sur la sant\u00e9 publique et potentiellement pr\u00e9venir les complications du COVID-19 chez des millions de patients \u00bb, a indiqu\u00e9 le Dr Jean-Claude Tardif.<\/p>\n

La prescription de la colchicine aux patients pourrait ainsi contribuer \u00e0 att\u00e9nuer les probl\u00e8mes d\u2019engorgement des h\u00f4pitaux et de r\u00e9duire les co\u00fbts li\u00e9s aux syst\u00e8mes de sant\u00e9 des gouvernements d\u2019ici comme ailleurs.<\/p>\n

\u00ab La colchicine est un puissant anti-inflammatoire avec un bon profil de s\u00e9curit\u00e9 d\u00e9j\u00e0 utilis\u00e9 pour le traitement de la goutte \u00bb, a, quant \u00e0 lui, affirm\u00e9 le Dr Guy Boivin, microbiologiste-infectiologue au CHU de Qu\u00e9bec et co-investigateur de l\u2019\u00e9tude.<\/p>\n","protected":false},"excerpt":{"rendered":"

Africa-Press – Niger. Les r\u00e9sultats de l\u2019\u00e9tude \u201cCOLCORONA\u201d ont montr\u00e9 que la colchicine est le seul m\u00e9dicament oral efficace pour traiter les patients non-hospitalis\u00e9s du COVID-19. L\u2019Institut de Cardiologie de Montr\u00e9al (ICM) a annonc\u00e9 le 22 janvier 2021 que l\u2019\u00e9tude COLCORONA a fourni des r\u00e9sultats cliniquement convaincants de l\u2019efficacit\u00e9 de la colchicine (alcalo\u00efde ou mol\u00e9cule […]<\/p>\n","protected":false},"author":82,"featured_media":2456,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[22,11,10],"tags":[84,55,60,72,82,83,29],"class_list":["post-2457","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divers","category-homepage-french","category-toutes-les-actualites","tag-cas-suspect-coronavirus","tag-africa-press","tag-africa-press-niger","tag-alerte-burkina-24","tag-coronavirus","tag-covid-19","tag-niger"],"yoast_head":"\nCOVID-19 : La colchicine r\u00e9duit le risque de complications (Etude COLCORONA) - niger<\/title>\n<meta name=\"description\" content=\"Les r\u00e9sultats de 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