{"id":11015,"date":"2024-01-02T19:26:51","date_gmt":"2024-01-02T19:26:51","guid":{"rendered":"https:\/\/www.africa-press.net\/sao-tome-e-principe\/politique\/les-attaques-toujours-plus-ciblees-de-limmunotherapie"},"modified":"2024-01-02T21:39:50","modified_gmt":"2024-01-02T21:39:50","slug":"les-attaques-toujours-plus-ciblees-de-limmunotherapie","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/sao-tome-e-principe\/toutes-les-actualites\/les-attaques-toujours-plus-ciblees-de-limmunotherapie","title":{"rendered":"Les attaques toujours plus cibl\u00e9es de l\u2019immunoth\u00e9rapie"},"content":{"rendered":"

Africa-Press – S\u00e3o Tom\u00e9 e Pr\u00edncipe. <\/strong><\/span>Alors qu\u2019elles devraient e\u0302tre attaque\u0301es et e\u0301limine\u0301es par le syste\u0300me immunitaire, comme toute cellule anormale, les cellules cance\u0301reuses sont capables de faire en sorte qu\u2019il les tole\u0300re, ce qui leur permet de prolife\u0301rer et de former des tumeurs. Stimuler le syste\u0300me immunitaire pour lui redonner son ro\u0302le de de\u0301fenseur de l\u2019organisme: tel est l\u2019objectif de l\u2019immunothe\u0301rapie, dont l\u2019essor remonte a\u0300 2010, et dont l\u2019action a de\u0301ja\u0300 permis d\u2019augmenter de fac\u0327on spectaculaire la survie de malades atteints de me\u0301lanome ou de cancer du poumon a\u0300 des stades avance\u0301s.<\/p>\n

Immunothe\u0301rapie 2.0<\/b><\/p>\n

Cette strate\u0301gie the\u0301rapeutique est expe\u0301rimente\u0301e pour des types de cancers de plus en plus nombreux. \u201cEt a\u0300 des stades plus pre\u0301coces, avant ou juste apre\u0300s la chirurgie\u201d, indique Aure\u0301lien Marabelle, qui dirige le programme de recherche sur l\u2019immunothe\u0301rapie au centre anti-cancer Gustave-Roussy, a\u0300 Villejuif (Val-de-Marne).<\/p>\n

Il conside\u0300re, enthousiaste, qu’\u201don est en train de passer a\u0300 l\u2019immunothe\u0301rapie 2.0\u2032\u2032. Autrement dit, de\u0300s lors qu\u2019on sait que \u201cl\u2019approche est pertinente pour traiter le cancer\u201d , on est entre\u0301 dans une deuxie\u0300me phase. \u201cLe syste\u0300me immunitaire rassemble des cellules tre\u0300s diffe\u0301rentes. On a donc la possibilite\u0301 d\u2019avoir un grand nombre de cibles, mais aussi diverses fac\u0327ons de diriger vers elles les me\u0301dicaments, ce qui est ine\u0301dit dans l\u2019histoire de la cance\u0301rologie\u201d, poursuit-il.<\/p>\n

De nombreuses utilisations possibles<\/b><\/p>\n

Aujourd\u2019hui, a\u0300 l\u2019ho\u0302pital, l\u2019immunothe\u0301rapie repose surtout sur l\u2019usage d\u2019anticorps monoclonaux, qui ciblent une prote\u0301ine de la membrane des cellules cance\u0301reuses. Mais demain, le spe\u0301cialiste de\u0301crit des anticorps bispe\u0301cifiques qui rapprochent physiquement la cellule immunitaire de la cellule cance\u0301reuse, ou encore des the\u0301rapies ge\u0301niques sous forme de cocktail d\u2019ARN, qui forceront la cellule cance\u0301reuse a\u0300 se\u0301cre\u0301ter des mole\u0301cules la rendant plus susceptible d\u2019activer le syste\u0300me immunitaire. Sans oublier les vaccins the\u0301rapeutiques qui font d\u2019ores et de\u0301ja\u0300 l\u2019objet d\u2019essais cliniques, notamment pour le cancer du pancre\u0301as au pronostic sombre.<\/p>\n

Pour plus d’informations et d’analyses sur la S\u00e3o Tom\u00e9 e Pr\u00edncipe<\/a>, suivez Africa-Press<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Africa-Press – S\u00e3o Tom\u00e9 e Pr\u00edncipe. Alors qu\u2019elles devraient e\u0302tre attaque\u0301es et e\u0301limine\u0301es par le syste\u0300me immunitaire, comme toute cellule anormale, les cellules cance\u0301reuses sont capables de faire en sorte qu\u2019il les tole\u0300re, ce qui leur permet de prolife\u0301rer et de former des tumeurs. Stimuler le syste\u0300me immunitaire pour lui redonner son ro\u0302le de de\u0301fenseur […]<\/p>\n","protected":false},"author":82,"featured_media":11014,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[22,10],"tags":[36,55,56],"class_list":["post-11015","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divers","category-toutes-les-actualites","tag-africa-press","tag-africa-press-sao-tome-e-principe","tag-sao-tome-e-principe"],"yoast_head":"\nLes attaques toujours plus cibl\u00e9es de l\u2019immunoth\u00e9rapie - S\u00e3o Tom\u00e9 e Pr\u00edncipe<\/title>\n<meta name=\"description\" content=\"Alors qu\u2019elles devraient e\u0302tre attaque\u0301es et e\u0301limine\u0301es par le syste\u0300me immunitaire, comme toute cellule anormale, les ...\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.africa-press.net\/sao-tome-e-principe\/toutes-les-actualites\/les-attaques-toujours-plus-ciblees-de-limmunotherapie\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Les attaques toujours plus cibl\u00e9es de l\u2019immunoth\u00e9rapie\" \/>\n<meta property=\"og:description\" content=\"Alors qu\u2019elles devraient e\u0302tre attaque\u0301es et e\u0301limine\u0301es par le syste\u0300me immunitaire, comme toute cellule anormale, les ...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.africa-press.net\/sao-tome-e-principe\/toutes-les-actualites\/les-attaques-toujours-plus-ciblees-de-limmunotherapie\" \/>\n<meta property=\"og:site_name\" content=\"S\u00e3o Tom\u00e9 e Pr\u00edncipe\" \/>\n<meta property=\"article:published_time\" content=\"2024-01-02T19:26:51+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-01-02T21:39:50+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/static.africa-press.net\/sao-tome-e-principe\/sites\/59\/2024\/01\/sm_1704215071.388002.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"900\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"cfeditorfr\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"cfeditorfr\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.africa-press.net\/sao-tome-e-principe\/toutes-les-actualites\/les-attaques-toujours-plus-ciblees-de-limmunotherapie#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.africa-press.net\/sao-tome-e-principe\/toutes-les-actualites\/les-attaques-toujours-plus-ciblees-de-limmunotherapie\"},\"author\":{\"name\":\"cfeditorfr\",\"@id\":\"https:\/\/www.africa-press.net\/sao-tome-e-principe\/#\/schema\/person\/2b1cf3cd81a31e3cd26889ca66d677f1\"},\"headline\":\"Les attaques toujours plus cibl\u00e9es de l\u2019immunoth\u00e9rapie\",\"datePublished\":\"2024-01-02T19:26:51+00:00\",\"dateModified\":\"2024-01-02T21:39:50+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.africa-press.net\/sao-tome-e-principe\/toutes-les-actualites\/les-attaques-toujours-plus-ciblees-de-limmunotherapie\"},\"wordCount\":408,\"commentCount\":0,\"image\":{\"@id\":\"https:\/\/www.africa-press.net\/sao-tome-e-principe\/toutes-les-actualites\/les-attaques-toujours-plus-ciblees-de-limmunotherapie#primaryimage\"},\"thumbnailUrl\":\"https:\/\/static.africa-press.net\/sao-tome-e-principe\/sites\/59\/2024\/01\/sm_1704215071.388002.jpg\",\"keywords\":[\"Africa Press\",\"Africa Press-S\u00e3o Tom\u00e9 e Pr\u00edncipe\",\"S\u00e3o Tom\u00e9 e Pr\u00edncipe\"],\"articleSection\":[\"Divers\",\"Toutes les actualit\u00e9s\"],\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.africa-press.net\/sao-tome-e-principe\/toutes-les-actualites\/les-attaques-toujours-plus-ciblees-de-limmunotherapie#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.africa-press.net\/sao-tome-e-principe\/toutes-les-actualites\/les-attaques-toujours-plus-ciblees-de-limmunotherapie\",\"url\":\"https:\/\/www.africa-press.net\/sao-tome-e-principe\/toutes-les-actualites\/les-attaques-toujours-plus-ciblees-de-limmunotherapie\",\"name\":\"Les attaques toujours plus cibl\u00e9es de l\u2019immunoth\u00e9rapie - 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