{"id":11233,"date":"2024-01-15T15:22:45","date_gmt":"2024-01-15T15:22:45","guid":{"rendered":"https:\/\/www.africa-press.net\/sao-tome-e-principe\/politique\/le-vieillissement-premature-de-nos-organes-detecte-dans-le-sang"},"modified":"2024-01-15T16:38:35","modified_gmt":"2024-01-15T16:38:35","slug":"le-vieillissement-premature-de-nos-organes-detecte-dans-le-sang","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/sao-tome-e-principe\/toutes-les-actualites\/le-vieillissement-premature-de-nos-organes-detecte-dans-le-sang","title":{"rendered":"Le vieillissement pr\u00e9matur\u00e9 de nos organes d\u00e9tect\u00e9 dans le sang"},"content":{"rendered":"

Africa-Press – S\u00e3o Tom\u00e9 e Pr\u00edncipe. <\/strong><\/span>Le dicton que l\u2019on a l\u2019a\u0302ge de ses arte\u0300res a e\u0301te\u0301 ve\u0301rifie\u0301 au niveau mole\u0301culaire et e\u0301largi a\u0300 d\u2019autres organes par des biologistes ame\u0301ricains de l\u2019universite\u0301 de Stanford (Etats-Unis). Les chercheurs ont montre\u0301 que chaque organe de notre corps libe\u0300re dans le sang un ensemble de prote\u0301ines caracte\u0301ristique de son a\u0302ge biologique. Ils ont publie\u0301 leurs re\u0301sultats dans la revue Nature.<\/p>\n

Une analyse par intelligence artificielle de 5000 prote\u0301ines<\/b><\/p>\n

Une analyse par intelligence artificielle (IA) de pre\u0300s de 5000 prote\u0301ines sanguines chez 5676 personnes a ainsi permis d\u2019en identifier 756 qui s\u2019ave\u0300rent plus spe\u0301cifiquement lie\u0301es a\u0300 un organe donne\u0301. Les chercheurs ont ensuite e\u0301tudie\u0301 l\u2019e\u0301volution avec l\u2019a\u0302ge du profil prote\u0301ique de 11 de ces organes. Leur vitesse de vieillissement est apparue inde\u0301pendante des autres et devenait supe\u0301rieure a\u0300 la moyenne en cas de pathologie de l\u2019organe.<\/p>\n

Le vieillissement pre\u0301mature\u0301 d\u2019un organe observe\u0301 chez pre\u0300s de 20% des personnes teste\u0301es<\/b><\/p>\n

Par exemple, le rein des diabe\u0301tiques ou des hypertendus e\u0301tait biologiquement plus vieux d\u2019un an que la moyenne, et cela inde\u0301pendamment de ses capacite\u0301s fonctionnelles. Pour le c\u0153ur, un a\u0302ge supe\u0301rieur de 4 ans au reste de l\u2019organisme chez une personne se traduisait par une multiplication par 2,5 du risque qu\u2019elle ait un accident cardiaque dans les 15 ans.<\/p>\n

Le vieillissement pre\u0301mature\u0301 d\u2019un organe a ainsi e\u0301te\u0301 observe\u0301 chez pre\u0300s de 20% des personnes teste\u0301es. Il concernait me\u0302me tous les organes chez les personnes ayant eu une attaque cardiaque ou atteintes de maladie d\u2019Alzheimer. Inversement, un vieillissement plus accentue\u0301 du cerveau e\u0301tait associe\u0301 a\u0300 un risque plus e\u0301leve\u0301 de pre\u0301senter un de\u0301but de maladie d\u2019Alzheimer par la suite. Les prote\u0301ines lie\u0301es a\u0300 un a\u0302ge avance\u0301 de chaque organe sont autant d\u2019indices sur les me\u0301canismes de son vieillissement et de pistes pour tenter de limiter ce dernier, indiquent les chercheurs.<\/p>\n

Pour plus d’informations et d’analyses sur la S\u00e3o Tom\u00e9 e Pr\u00edncipe<\/a>, suivez Africa-Press<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Africa-Press – S\u00e3o Tom\u00e9 e Pr\u00edncipe. Le dicton que l\u2019on a l\u2019a\u0302ge de ses arte\u0300res a e\u0301te\u0301 ve\u0301rifie\u0301 au niveau mole\u0301culaire et e\u0301largi a\u0300 d\u2019autres organes par des biologistes ame\u0301ricains de l\u2019universite\u0301 de Stanford (Etats-Unis). Les chercheurs ont montre\u0301 que chaque organe de notre corps libe\u0300re dans le sang un ensemble de prote\u0301ines caracte\u0301ristique de […]<\/p>\n","protected":false},"author":82,"featured_media":11232,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[22,10],"tags":[36,55,56],"class_list":["post-11233","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divers","category-toutes-les-actualites","tag-africa-press","tag-africa-press-sao-tome-e-principe","tag-sao-tome-e-principe"],"yoast_head":"\nLe vieillissement pr\u00e9matur\u00e9 de nos organes d\u00e9tect\u00e9 dans le sang - S\u00e3o Tom\u00e9 e Pr\u00edncipe<\/title>\n<meta name=\"description\" content=\"Le dicton que l\u2019on a l\u2019a\u0302ge de ses arte\u0300res a e\u0301te\u0301 ve\u0301rifie\u0301 au niveau mole\u0301culaire et e\u0301largi a\u0300 d\u2019autres organes par ...\" \/>\n<meta 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