{"id":12646,"date":"2024-03-26T12:52:49","date_gmt":"2024-03-26T12:52:49","guid":{"rendered":"https:\/\/www.africa-press.net\/sao-tome-e-principe\/politique\/decouverte-dune-bacterie-impliquee-dans-le-cancer-de-lestomac"},"modified":"2024-03-27T23:10:20","modified_gmt":"2024-03-27T23:10:20","slug":"decouverte-dune-bacterie-impliquee-dans-le-cancer-de-lestomac","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/sao-tome-e-principe\/toutes-les-actualites\/decouverte-dune-bacterie-impliquee-dans-le-cancer-de-lestomac","title":{"rendered":"D\u00e9couverte d\u2019une bact\u00e9rie impliqu\u00e9e dans le cancer de l\u2019estomac"},"content":{"rendered":"

Africa-Press – S\u00e3o Tom\u00e9 e Pr\u00edncipe. <\/strong><\/span>Helicobacter pylori, seule bacte\u0301rie responsable des cancers gastriques ? Une nouvelle e\u0301tude le de\u0301ment et met en e\u0301vidence une autre bacte\u0301rie commune implique\u0301e dans le risque de cancer de l\u2019estomac. Les chercheurs ont identifie\u0301 son me\u0301canisme d\u2019action, ce qui ouvre la voie a\u0300 la mise au point de traitements visant a\u0300 re\u0301duire ce risque.<\/p>\n

Une nouvelle e\u0301tude de l\u2019universite\u0301 technologique de Nanyang a\u0300 Singapour et de l\u2019universite\u0301 chinoise de Hong Kong sugge\u0300re que deux bacte\u0301ries communes pourraient agir ensemble pour favoriser l\u2019apparition d\u2019un cancer de l\u2019estomac. La premie\u0300re, Helicobacter pylori, est de\u0301ja\u0300 connue pour provoquer une infection qui augmente le risque de cancer de l\u2019estomac lorsqu\u2019elle devient pathoge\u0300ne.<\/p>\n

Toutefois, seules 1 a\u0300 3 % des personnes infecte\u0301es par la bacte\u0301rie de\u0301veloppent le cancer. Les chercheurs ont donc examine\u0301 le microbiote intestinal (hors H. pylori) chez des patients a\u0300 diffe\u0301rents stades du cancer gastrique pour identifier une autre bacte\u0301rie susceptible de favoriser l\u2019apparition du cancer.<\/p>\n

Parmi les cinq pathoge\u0300nes oraux fortement pre\u0301sents dans les muqueuses gastriques de ces patients, Streptococcus anginosus s\u2019est de\u0301marque\u0301e. Cette bacte\u0301rie de\u0301ja\u0300 pre\u0301sente dans la bouche, la gorge, les intestins et le vagin peut engendrer des infections be\u0301nignes lorsque le syste\u0300me immunitaire est affaibli.<\/p>\n

Streptococcus anginosus induit une inflammation gastrique progressive<\/b><\/p>\n

Les expe\u0301riences mene\u0301es chez la souris ont montre\u0301 que la colonisation de l\u2019estomac par S. anginosus de\u0301clenche une re\u0301ponse inflammatoire aigue\u0308, puis chronique. \u00ab L\u2019infection par S. anginosus a spontane\u0301ment induit une gastrite chronique progressive, une atrophie des cellules parie\u0301tales, une me\u0301taplasie mucineuse et une dysplasie chez les souris \u00bb, e\u0301crivent les auteurs de l\u2019e\u0301tude publie\u0301e dans la revue Cell.<\/p>\n

Les chercheurs ont e\u0301galement trouve\u0301 que la perturbation d\u2019une prote\u0301ine a\u0300 la surface de S. anginosus \u2014 dont elle a besoin pour communiquer avec les cellules de la muqueuse de l\u2019estomac \u2014 diminuait sa capacite\u0301 a\u0300 contribuer au cancer de l\u2019estomac, ce qui pourrait repre\u0301senter une piste the\u0301rapeutique inte\u0301ressante.<\/p>\n

Pour plus d’informations et d’analyses sur la S\u00e3o Tom\u00e9 e Pr\u00edncipe<\/a>, suivez Africa-Press<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Africa-Press – S\u00e3o Tom\u00e9 e Pr\u00edncipe. Helicobacter pylori, seule bacte\u0301rie responsable des cancers gastriques ? Une nouvelle e\u0301tude le de\u0301ment et met en e\u0301vidence une autre bacte\u0301rie commune implique\u0301e dans le risque de cancer de l\u2019estomac. Les chercheurs ont identifie\u0301 son me\u0301canisme d\u2019action, ce qui ouvre la voie a\u0300 la mise au point de traitements […]<\/p>\n","protected":false},"author":82,"featured_media":12645,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[22,10],"tags":[36,55,56],"class_list":["post-12646","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divers","category-toutes-les-actualites","tag-africa-press","tag-africa-press-sao-tome-e-principe","tag-sao-tome-e-principe"],"yoast_head":"\nD\u00e9couverte d\u2019une bact\u00e9rie impliqu\u00e9e dans le cancer de l\u2019estomac - S\u00e3o Tom\u00e9 e Pr\u00edncipe<\/title>\n<meta name=\"description\" content=\"Helicobacter pylori, seule bacte\u0301rie responsable des cancers gastriques ? 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