{"id":45409,"date":"2023-06-05T21:04:55","date_gmt":"2023-06-05T21:04:55","guid":{"rendered":"https:\/\/www.africa-press.net\/senegal\/politique\/asco-2023-cancer-du-poumon-un-traitement-reduit-significativement-le-risque-de-deces"},"modified":"2023-06-05T22:18:04","modified_gmt":"2023-06-05T22:18:04","slug":"asco-2023-cancer-du-poumon-un-traitement-reduit-significativement-le-risque-de-deces","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/senegal\/toutes-les-actualites\/asco-2023-cancer-du-poumon-un-traitement-reduit-significativement-le-risque-de-deces","title":{"rendered":"ASCO 2023. Cancer du poumon\u00a0: un traitement r\u00e9duit significativement le risque de d\u00e9c\u00e8s"},"content":{"rendered":"

Africa-Press – Senegal. <\/strong><\/span>Les bonnes nouvelles en matie\u0300re de cancer du poumon, c\u2019est parfois possible. La preuve avec une pre\u0301sentation durant le premier week-end de juin 2023 et tre\u0300s applaudie en se\u0301ance ple\u0301nie\u0300re a\u0300 l\u2019occasion de l\u2019ASCO 2023 (American Society of Clinical Oncology), le plus grand congre\u0300s international de cance\u0301rologie qui se de\u0301roule du 2 au 6 juin 2023 a\u0300 Chicago et re\u0301unit plus de 30.000 spe\u0301cialistes.<\/p>\n

Un traitement pour les patients atteints de la forme la plus commune de cancer du poumon<\/b><\/p>\n

Cette annonce orale a e\u0301te\u0301 de plus accompagne\u0301e par une publication simultane\u0301e dans le New England Journal of Medicine, ce qui vient e\u0301videmment renforcer l\u2019importance de son re\u0301sultat. Elle concerne les patients atteints d\u2019un cancer dit \u201cnon a\u0300 petites cellules\u201d, la forme la plus commune de ce type de cancer, pre\u0301sentant un type particulier de mutation, dit de type Egfr, soit environ 10 % a\u0300 25 % des patients aux E\u0301tats-Unis et en Europe, 30 % a\u0300 40 % en Asie.<\/p>\n

Une fois ope\u0301re\u0301s car repe\u0301re\u0301s a\u0300 un stade pre\u0301coce, les patients inclus dans l\u2019essai Adaura (environ 700 malades re\u0301partis dans une vingtaine de pays) ont e\u0301te\u0301 divise\u0301s en deux groupes.<\/p>\n

Apre\u0300s l\u2019intervention chirurgicale, ils ont pris, en plus de la chimiothe\u0301rapie et pendant trois ans, et de manie\u0300re quotidienne : soit une the\u0301rapie cible\u0301e, l\u2019osimertinib (Tagrisso, du laboratoire AstraZeneca) commercialise\u0301e sous forme d\u2019un comprime\u0301, une mole\u0301cule de la famille dite des inhibiteurs de tyrosine kinase ; soit un placebo.<\/p>\n

Un traitement qui re\u0301duit de moitie\u0301 le risque de de\u0301ce\u0300s par cancer sur cinq ans<\/b><\/p>\n

Le re\u0301sultat est sans appel : ce traitement a permis de re\u0301duire de moitie\u0301 le risque de de\u0301ce\u0300s par cancer dans le groupe ayant rec\u0327u la the\u0301rapie cible\u0301e. En clair, apre\u0300s cinq ans, 88 % des patients du groupe Tagrisso e\u0301taient toujours vivants, contre 78 % dans le groupe placebo.<\/p>\n

Un re\u0301sultat qualifie\u0301 \u201cd\u2019ame\u0301lioration sans e\u0301quivoque et hautement cliniquement significative de la survie globale a\u0300 cinq ans\u201d, par Nathan Pennell, codirecteur du programme de lutte contre le cancer du poumon de la Cleveland Clinic (Ohio, Etats-Unis) lors d\u2019un point presse. De\u0301ja\u0300 autorise\u0301e dans diffe\u0301rents pays, la mole\u0301cule avait de\u0301ja\u0300 de\u0301montre\u0301 son inte\u0301re\u0302t en ame\u0301liorant la survie sans re\u0301cidive de la maladie, mais cette fois, ce sont les donne\u0301es de survie globale qui ont e\u0301te\u0301 communique\u0301es. Un re\u0301sultat qui renforce la ne\u0301cessite\u0301 de la recherche syste\u0301matique face a\u0300 un cancer pulmonaire de la mutation EGFR pour e\u0301viter les pertes de chance des patients e\u0301ligibles au traitement.<\/p>\n

Pour plus d’informations et d’analyses sur la Senegal<\/a>, suivez Africa-Press<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Africa-Press – Senegal. Les bonnes nouvelles en matie\u0300re de cancer du poumon, c\u2019est parfois possible. La preuve avec une pre\u0301sentation durant le premier week-end de juin 2023 et tre\u0300s applaudie en se\u0301ance ple\u0301nie\u0300re a\u0300 l\u2019occasion de l\u2019ASCO 2023 (American Society of Clinical Oncology), le plus grand congre\u0300s international de cance\u0301rologie qui se de\u0301roule du 2 […]<\/p>\n","protected":false},"author":82,"featured_media":45408,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[22,10],"tags":[43,47,44],"class_list":["post-45409","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divers","category-toutes-les-actualites","tag-africa-press-2","tag-africa-press-senegal","tag-senegal-2"],"yoast_head":"\nASCO 2023. 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