{"id":71423,"date":"2025-09-29T12:00:00","date_gmt":"2025-09-29T12:00:00","guid":{"rendered":"https:\/\/www.africa-press.net\/senegal\/politique\/vers-un-implant-pour-soigner-la-polyarthrite-rhumatoide"},"modified":"2025-09-30T04:08:09","modified_gmt":"2025-09-30T04:08:09","slug":"vers-un-implant-pour-soigner-la-polyarthrite-rhumatoide","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/senegal\/toutes-les-actualites\/vers-un-implant-pour-soigner-la-polyarthrite-rhumatoide","title":{"rendered":"Vers un Implant pour Soigner la Polyarthrite Rhumatoi\u0308De?"},"content":{"rendered":"

Africa-Press – Senegal. <\/strong><\/span>Vous connaissez le nerf vague, ce fameux nerf \u00ab miracle \u00bb reliant intestin et cerveau dont la stimulation e\u0301lectrique fait depuis de\u0301ja\u0300 plusieurs anne\u0301es couler beaucoup d\u2019encre? Epilepsie re\u0301fractaire, de\u0301pression, maladie de Crohn, migraines, douleurs chroniques, diabe\u0300te, arthrose, scle\u0301rose en plaques, re\u0301cupe\u0301ration apre\u0300s un accident vasculaire ce\u0301re\u0301bral (AVC)… la liste des affections potentiellement concerne\u0301es par sa stimulation ne cesse de s\u2019allonger.<\/p>\n

Pourquoi une liste aussi he\u0301te\u0301roge\u0300ne? Parce qu\u2019apre\u0300s plusieurs de\u0301cennies de recherches, et me\u0302me si les me\u0301canismes pre\u0301cis des effets de la stimulation de ce 10e nerf cra\u0302nien restent encore mal compris, nombreux sont les travaux de\u0301montrant que son activation re\u0301duit l\u2019inflammation syste\u0301mique mais aussi la douleur, mettant en lumie\u0300re une relation complexe entre les syste\u0300mes nerveux et immunitaire.<\/p>\n

Exemple ici avec la polyarthrite rhumatoi\u0308de, une maladie inflammatoire auto-immune chronique entrai\u0302nant douleur, gonflement et, a\u0300 terme, une destruction articulaire caracte\u0301rise\u0301e par une inflammation synoviale persistante. Cette dernie\u0300re conduit a\u0300 une e\u0301rosion osseuse et a\u0300 une de\u0301formation articulaire.<\/p>\n

Depuis de premiers essais communique\u0301s de\u0300s 2019 lors d\u2019un congre\u0300s international, nombreuses sont les e\u0301quipes a\u0300 s\u2019e\u0302tre inte\u0301resse\u0301es au potentiel de la stimulation vagale tout particulie\u0300rement pour cette maladie e\u0301voluant par pousse\u0301es capricieuses. Car si son traitement est a\u0300 ce jour purement me\u0301dical, la maladie, re\u0301sistante aux me\u0301dicaments immunosuppresseurs, reste souvent difficile a\u0300 traiter. Ce sont donc les chercheurs de la firme Set Point Me\u0301dical qui ont e\u0301te\u0301 les plus rapides, avec la mise au point d\u2019un implant sous-cutane\u0301.<\/p>\n

Une puce d\u2019environ 2,5 cm de long<\/b><\/p>\n

Comme l\u2019a annonce\u0301 cet e\u0301te\u0301 le magazine New Scientist, il s\u2019agit la\u0300 d\u2019une alternative originale au traitement me\u0301dical avec ici une approche radicalement diffe\u0301rente. Et c\u2019est la premie\u0300re fois qu\u2019un traitement non me\u0301dicamenteux est propose\u0301 pour cette affection. En effet, la Food and Drug administration (FDA) vient de donner son feu vert a\u0300 ce nouveau dispositif totalement implantable, utilisant des signaux e\u0301lectriques pour contro\u0302ler l\u2019inflammation.<\/p>\n

Avec cette nouvelle approche, tout repose sur une puce d\u2019environ 2,5 cm de long implante\u0301e chirurgicalement sous la peau du cou du patient pour envoyer au fameux nerf des stimulations e\u0301lectriques re\u0301gulie\u0300res pendant une minute par jour. Mene\u0301e par Set Point Medical, une e\u0301tude de phase 2, RESET-RA, pre\u0301sente\u0301e l\u2019an dernier au congre\u0300s ame\u0301ricain de rhumatologie s\u2019e\u0301tait ave\u0301re\u0301e encourageante aupre\u0300s d\u2019environ 250 patients suivis pendant un an apre\u0300s la pose de l\u2019implant. Plus de la moitie\u0301 d\u2019entre eux avaient constate\u0301 une ame\u0301lioration de leur e\u0301tat de sante\u0301, trois quarts d\u2019entre eux ayant pu interrompre leur traitement de fond.<\/p>\n

Depuis, la firme avait de\u0301pose\u0301 son dossier a\u0300 la FDA et les e\u0301tapes re\u0301glementaires ont suivi jusqu\u2019a\u0300 ce feu vert. Selon un porte-parole cite\u0301 par le New York Times, le dispositif cou\u0302terait moins cher qu\u2019un an de certains traitements actuels et pourrait durer jusqu\u2019a\u0300 dix ans. Reste encore toutefois a\u0300 de\u0301montrer l\u2019efficacite\u0301 et la se\u0301curite\u0301 sur le long terme de ce dispositif qui ne sont pas encore connues et qui devront e\u0302tre valide\u0301es par un essai clinique du\u0302ment publie\u0301. La FDA a pour sa part exige\u0301 un suivi post-commercialisation des patients et des effets inde\u0301sirables dans le cadre de son approbation estivale.<\/p>\n

Pour plus d’informations et d’analyses sur la Senegal<\/span>, suivez Africa-Press<\/span><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Africa-Press – Senegal. Vous connaissez le nerf vague, ce fameux nerf \u00ab miracle \u00bb reliant intestin et cerveau dont la stimulation e\u0301lectrique fait depuis de\u0301ja\u0300 plusieurs anne\u0301es couler beaucoup d\u2019encre? Epilepsie re\u0301fractaire, de\u0301pression, maladie de Crohn, migraines, douleurs chroniques, diabe\u0300te, arthrose, scle\u0301rose en plaques, re\u0301cupe\u0301ration apre\u0300s un accident vasculaire ce\u0301re\u0301bral (AVC)… la liste des affections […]<\/p>\n","protected":false},"author":82,"featured_media":71422,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[22,10],"tags":[44],"class_list":["post-71423","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divers","category-toutes-les-actualites","tag-senegal-2"],"yoast_head":"\nVers un Implant pour Soigner la Polyarthrite Rhumatoi\u0308De? - Senegal<\/title>\n<meta name=\"description\" content=\"Vous connaissez le nerf vague, ce fameux nerf \u00ab miracle \u00bb reliant intestin et cerveau dont la stimulation e\u0301lectrique fa ...\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.africa-press.net\/senegal\/toutes-les-actualites\/vers-un-implant-pour-soigner-la-polyarthrite-rhumatoide\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vers un Implant pour Soigner la Polyarthrite Rhumatoi\u0308De?\" \/>\n<meta property=\"og:description\" content=\"Vous connaissez le nerf vague, ce fameux nerf \u00ab miracle \u00bb reliant intestin et cerveau dont la stimulation e\u0301lectrique fa ...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.africa-press.net\/senegal\/toutes-les-actualites\/vers-un-implant-pour-soigner-la-polyarthrite-rhumatoide\" \/>\n<meta property=\"og:site_name\" content=\"Senegal\" \/>\n<meta property=\"article:published_time\" content=\"2025-09-29T12:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-09-30T04:08:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/static.africa-press.net\/senegal\/sites\/13\/2025\/09\/sm_1759232216.572597.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"720\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"cfeditorfr\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"cfeditorfr\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.africa-press.net\/senegal\/toutes-les-actualites\/vers-un-implant-pour-soigner-la-polyarthrite-rhumatoide#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.africa-press.net\/senegal\/toutes-les-actualites\/vers-un-implant-pour-soigner-la-polyarthrite-rhumatoide\"},\"author\":{\"name\":\"cfeditorfr\",\"@id\":\"https:\/\/www.africa-press.net\/senegal\/#\/schema\/person\/2b1cf3cd81a31e3cd26889ca66d677f1\"},\"headline\":\"Vers un Implant pour Soigner la Polyarthrite Rhumatoi\u0308De?\",\"datePublished\":\"2025-09-29T12:00:00+00:00\",\"dateModified\":\"2025-09-30T04:08:09+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.africa-press.net\/senegal\/toutes-les-actualites\/vers-un-implant-pour-soigner-la-polyarthrite-rhumatoide\"},\"wordCount\":633,\"commentCount\":0,\"image\":{\"@id\":\"https:\/\/www.africa-press.net\/senegal\/toutes-les-actualites\/vers-un-implant-pour-soigner-la-polyarthrite-rhumatoide#primaryimage\"},\"thumbnailUrl\":\"https:\/\/static.africa-press.net\/senegal\/sites\/13\/2025\/09\/sm_1759232216.572597.jpg\",\"keywords\":[\"Senegal\"],\"articleSection\":[\"Divers\",\"Toutes les actualit\u00e9s\"],\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.africa-press.net\/senegal\/toutes-les-actualites\/vers-un-implant-pour-soigner-la-polyarthrite-rhumatoide#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.africa-press.net\/senegal\/toutes-les-actualites\/vers-un-implant-pour-soigner-la-polyarthrite-rhumatoide\",\"url\":\"https:\/\/www.africa-press.net\/senegal\/toutes-les-actualites\/vers-un-implant-pour-soigner-la-polyarthrite-rhumatoide\",\"name\":\"Vers un Implant pour Soigner la Polyarthrite Rhumatoi\u0308De? 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