{"id":63070,"date":"2024-03-21T13:06:14","date_gmt":"2024-03-21T13:06:14","guid":{"rendered":"https:\/\/www.africa-press.net\/south-africa\/all-news\/hope-for-a-cure-scientists-successfully-remove-hiv-from-cells"},"modified":"2024-03-21T13:47:21","modified_gmt":"2024-03-21T13:47:21","slug":"hope-for-a-cure-scientists-successfully-remove-hiv-from-cells","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/south-africa\/all-news\/hope-for-a-cure-scientists-successfully-remove-hiv-from-cells","title":{"rendered":"Hope for a Cure: Scientists Successfully Remove HIV From Cells"},"content":{"rendered":"<p><span style=\"color: #ff6600\"><strong>Africa-Press &#8211; South-Africa. <\/strong><\/span>A 2020 Nobel Prize-winning gene-editing method promises to advance the cure of HIV, halting the need for long-term antiviral medication. However, challenges remain around the complexity of eradicating HIV from all infected cells.<\/p>\n<p>Researchers have successfully removed HIV from infected cells using a novel technique, raising hopes of a cure.<\/p>\n<p>The team was also able to pick out \u201chidden\u201d HIV storage cells, focusing on distinct proteins lodged on these cell surfaces.<\/p>\n<p>Scientists from the University of Amsterdam employed the Nobel Prize winning gene-editing tool CRISPR\/Cas9.<\/p>\n<p>The gene editor is used to change animal, plant, and microorganism DNAs with extremely high precision. This technology has revolutionized molecular life sciences, opened new plant-breeding opportunities, and contributed to the development of new cancer therapies.<\/p>\n<p>The tool functions like a cookie cutter, targeting HIV DNA at a microscopic level and cutting out all viral imprints at specific points in infected cells. This enables the elimination of unwanted genes or the introduction of new genetic materials into cells.<\/p>\n<p>Drafting their pre-conference abstract for the forthcoming 34th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024), the researchers disclosed that their work is a \u201cproof of concept.\u201d<\/p>\n<p>\u201cthese findings represent a pivotal advancement towards designing a cure strategy,\u201d they said.<\/p>\n<p>Molecular virologist and the study\u2019s lead author, <b>Dr Elena Herrera Carrillo from<\/b> Amsterdam University Medical Center, said that they aim to offer a therapy that can tackle multiple HIV strains effectively.<\/p>\n<p>The research findings stand out from several advances in the field. In 2023, the method was successfully applied to monkeys, paving the way for initial human trials.<\/p>\n<p>Other scientific endeavors have explored using CRISPR\/Cas9 against HIV. In one of such undertaking, Excision BioTherapies disclosed that after 48 weeks, three HIV-positive participants showed no concerning side effects.<\/p>\n<p>However, a virus expert, Dr. Jonathan Stoye, at the Francis Crick Institute, London, told the press that eliminating HIV from all the infected cells in the body was \u201cextremely challenging.\u201d<\/p>\n<p>He stressed that \u201cIt therefore seems likely that many years will elapse before any such Crispr-based therapy becomes routine \u2014 even assuming that it can be shown to be effective.&#8221;<\/p>\n<p>HIV infects immune system cells, hijacking their genetic replication system to make copies of itself. Despite effective treatment, some cells enter a form of hibernation, harboring HIV DNA without actively producing a new virus.<\/p>\n<p><strong>For More News And Analysis About <a href=\"https:\/\/www.africa-press.net\/south-africa\">South-Africa<\/a> Follow <a href=\"https:\/\/www.africa-press.net\/\">Africa-Press<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Africa-Press &#8211; South-Africa. A 2020 Nobel Prize-winning gene-editing method promises to advance the cure of HIV, halting the need for long-term antiviral medication. However, challenges remain around the complexity of eradicating HIV from all infected cells. Researchers have successfully removed HIV from infected cells using a novel technique, raising hopes of a cure. The team [&hellip;]<\/p>\n","protected":false},"author":84,"featured_media":63069,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,9],"tags":[274,315,275],"class_list":["post-63070","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-all-news","category-miscellaneous","tag-africa-press","tag-africa-press-south-africa","tag-south-africa-2"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.1 (Yoast SEO v27.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Hope for a Cure: Scientists Successfully Remove HIV From Cells - South Africa<\/title>\n<meta name=\"description\" content=\"A 2020 Nobel Prize-winning gene-editing method promises to advance the cure of HIV, halting the need for long-term antiv ...\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.africa-press.net\/south-africa\/all-news\/hope-for-a-cure-scientists-successfully-remove-hiv-from-cells\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hope for a Cure: Scientists Successfully Remove HIV From Cells\" \/>\n<meta property=\"og:description\" content=\"A 2020 Nobel Prize-winning gene-editing method promises to advance the cure of HIV, halting the need for long-term antiv ...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.africa-press.net\/south-africa\/all-news\/hope-for-a-cure-scientists-successfully-remove-hiv-from-cells\" \/>\n<meta property=\"og:site_name\" content=\"South Africa\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/AfricaPressTunisiaa\" \/>\n<meta property=\"article:published_time\" content=\"2024-03-21T13:06:14+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-03-21T13:47:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/static.africa-press.net\/south-africa\/sites\/31\/2024\/03\/sm_1711016130.861985.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1440\" \/>\n\t<meta property=\"og:image:height\" content=\"812\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"cfeditoren\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"cfeditoren\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.africa-press.net\/south-africa\/all-news\/hope-for-a-cure-scientists-successfully-remove-hiv-from-cells#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.africa-press.net\/south-africa\/all-news\/hope-for-a-cure-scientists-successfully-remove-hiv-from-cells\"},\"author\":{\"name\":\"cfeditoren\",\"@id\":\"https:\/\/www.africa-press.net\/south-africa\/#\/schema\/person\/068c7ab4e9634ae78ec5d54ec46598bb\"},\"headline\":\"Hope for a Cure: Scientists Successfully Remove HIV From Cells\",\"datePublished\":\"2024-03-21T13:06:14+00:00\",\"dateModified\":\"2024-03-21T13:47:21+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.africa-press.net\/south-africa\/all-news\/hope-for-a-cure-scientists-successfully-remove-hiv-from-cells\"},\"wordCount\":406,\"commentCount\":0,\"image\":{\"@id\":\"https:\/\/www.africa-press.net\/south-africa\/all-news\/hope-for-a-cure-scientists-successfully-remove-hiv-from-cells#primaryimage\"},\"thumbnailUrl\":\"https:\/\/static.africa-press.net\/south-africa\/sites\/31\/2024\/03\/sm_1711016130.861985.jpg\",\"keywords\":[\"Africa Press\",\"Africa Press-South-Africa\",\"South-Africa\"],\"articleSection\":[\"all news\",\"miscellaneous\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.africa-press.net\/south-africa\/all-news\/hope-for-a-cure-scientists-successfully-remove-hiv-from-cells#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.africa-press.net\/south-africa\/all-news\/hope-for-a-cure-scientists-successfully-remove-hiv-from-cells\",\"url\":\"https:\/\/www.africa-press.net\/south-africa\/all-news\/hope-for-a-cure-scientists-successfully-remove-hiv-from-cells\",\"name\":\"Hope for a Cure: Scientists Successfully Remove HIV From Cells - 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