{"id":22939,"date":"2023-07-20T11:00:00","date_gmt":"2023-07-20T11:00:00","guid":{"rendered":"https:\/\/www.africa-press.net\/togo\/politique\/une-equipe-allemande-developpe-le-premier-ventricule-artificiel-battant"},"modified":"2023-07-22T21:35:03","modified_gmt":"2023-07-22T21:35:03","slug":"une-equipe-allemande-developpe-le-premier-ventricule-artificiel-battant","status":"publish","type":"post","link":"https:\/\/www.africa-press.net\/togo\/toutes-les-actualites\/une-equipe-allemande-developpe-le-premier-ventricule-artificiel-battant","title":{"rendered":"Une \u00e9quipe allemande d\u00e9veloppe le premier ventricule artificiel battant"},"content":{"rendered":"

Africa-Press – Togo. <\/strong><\/span>Nouvelle e\u0301tape dans la (tre\u0300s) longue marche vers le c\u0153ur artificiel autonome. Des scientifiques de l\u2019Universite\u0301 Friedrich-Alexander d\u2019Erlangen-Nuremberg (Allemagne) ont de\u0301montre\u0301, avec une re\u0301cente e\u0301tude en pre\u0301publication (article scientifique non relu par les pairs) sur le site BioRxiv, que le nouveau dispositif d\u2019impression tissulaire qu\u2019ils ont e\u0301tabli a permis d\u2019obtenir de ve\u0301ritables ventricules miniatures artificiels. Ces derniers ont tous la capacite\u0301 de se contracter spontane\u0301ment et ce, pendant plus de 100 jours conse\u0301cutifs. Une premie\u0300re, me\u0302me si d\u2019autres travaux, comme ceux proches de chercheurs israe\u0301liens conduits en 2019, e\u0301taient parvenus a\u0300 imprimer en 3D un c\u0153ur entier mais non battant.<\/p>\n

Six fois plus petits que de ve\u0301ritables ventricules humains<\/b><\/p>\n

Ici, ce nouveau travail a consiste\u0301 a\u0300 cre\u0301er une \u00ab\u00a0bioencre\u00a0\u00bb faite de cellules cardiaques, des cardiomyocytes de\u0301rive\u0301s de cellules souches pluripotentes induites par l\u2019homme (hiPSC-CM), et a\u0300 l\u2019associer a\u0300 un gel compose\u0301 de collage\u0300ne et d\u2019acide hayluronique. C\u2019est justement cette combinaison qui a permis la production des ventricules artificiels (voir photo) miniatures, d\u2019environ 14 mm de haut et 8 de diame\u0300tre, soit six fois plus petits que de ve\u0301ritables ventricules humains.<\/p>\n

Ventricule imprime\u0301 non contracte\u0301 et contracte\u0301. Cre\u0301dit : Tilman U. Esser & all (BioRxiv)<\/p>\n

Des ame\u0301liorations attendues<\/b><\/p>\n

Ces \u00ab\u00a0petits ballons de baudruche\u00a0\u00bb posse\u0300dent une particularite\u0301, celle d\u2019e\u0302tre fonctionnels, c\u2019est-a\u0300-dire en capacite\u0301 de battre en continu et de manie\u0300re autonome, ici plus de 3 mois. Toutefois, un c\u0153ur ne se limite pas a\u0300 une seule cavite\u0301 mais a\u0300 quatre, soit au total deux oreillettes et deux ventricules. Un impe\u0301ratif anatomique qui guidera les travaux pre\u0301vus a\u0300 l’avenir par l’e\u0301quipe, soit la transposition du protocole a\u0300 un c\u0153ur entier.<\/p>\n

Pour plus d’informations et d’analyses sur la Togo<\/a>, suivez Africa-Press<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Africa-Press – Togo. Nouvelle e\u0301tape dans la (tre\u0300s) longue marche vers le c\u0153ur artificiel autonome. Des scientifiques de l\u2019Universite\u0301 Friedrich-Alexander d\u2019Erlangen-Nuremberg (Allemagne) ont de\u0301montre\u0301, avec une re\u0301cente e\u0301tude en pre\u0301publication (article scientifique non relu par les pairs) sur le site BioRxiv, que le nouveau dispositif d\u2019impression tissulaire qu\u2019ils ont e\u0301tabli a permis d\u2019obtenir de ve\u0301ritables […]<\/p>\n","protected":false},"author":82,"featured_media":22938,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[22,10],"tags":[36,49,50],"class_list":["post-22939","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divers","category-toutes-les-actualites","tag-africa-press","tag-africa-press-togo","tag-togo"],"yoast_head":"\nUne \u00e9quipe allemande d\u00e9veloppe le premier ventricule artificiel battant - Togo<\/title>\n<meta name=\"description\" content=\"Nouvelle e\u0301tape dans la (tre\u0300s) longue marche vers le c\u0153ur artificiel autonome. 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